Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | PDXK | O00764 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5364590 | 0.87 | KDM4E (0.58) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL5351375 | 0.81 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL405403 | 0.80 | HPGD (0.63) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL29906194 | 0.80 | HPGD (0.55) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL5346682 | 0.79 | KDM4E (0.61) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL24248105 | 0.76 | HPGD (0.65) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL1983313 | 0.75 | KDM4E (0.60) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL31306175 | 0.75 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| Pyridoxine SCHEMBL5364587 | 0.74 | KDM4E (0.73) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL21916171 | 0.74 | PNPO (0.38) | KDM4EALDH1A1HPGDHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156648-A1 | Preparations containing pyridoxine and alpha-hydroxyisocaproic acid (HICA) | IOVATE T. & P. INC. (CA) | 2009-06-18 | — | — | US | claimed |
| US-20090156647-A1 | Method for maintaining physiological pH levels during intensive physical exercise | IOVATE T. & P. INC. (CA) | 2009-06-18 | — | — | US | claimed |
| EP-2231604-A1 | PREPARATIONS CONTAINING PYRIDOXINE AND ALPHA-HYDROXYISOCAPROIC ACID (HICA) | Northern Innovations and Formulations Corp. (CA) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009073944-A1 | USE OF PYRIDOXINE α-HYDROXYISOCAPROATE TO REDUCE METABOLIC ACIDOSIS AND AMMONIA ACCUMULATION | IOVATE T. & P. INC. (CA) | 2009-06-18 | — | — | WO | disclosed |
| WO-2009073944-A1 | USE OF PYRIDOXINE α-HYDROXYISOCAPROATE TO REDUCE METABOLIC ACIDOSIS AND AMMONIA ACCUMULATION | IOVATE T. & P. INC. (CA) | 2009-06-18 | — | — | WO | disclosed |
| WO-2009073943-A1 | PREPARATIONS CONTAINING PYRIDOXINE AND ALPHA-HYDROXYISOCAPROIC ACID (HICA) | IOVATE T. & P. INC. (CA) | 2009-06-18 | — | — | WO | disclosed |
| US-20090156648-A1 | Preparations containing pyridoxine and alpha-hydroxyisocaproic acid (HICA) | IOVATE T. & P. INC. (CA) | 2009-06-18 | — | — | US | disclosed |
| US-20090156647-A1 | Method for maintaining physiological pH levels during intensive physical exercise | IOVATE T. & P. INC. (CA) | 2009-06-18 | — | — | US | disclosed |
| US-20090156647-A1 | Method for maintaining physiological pH levels during intensive physical exercise | IOVATE T. & P. INC. (CA) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156648-A1 | Preparations containing pyridoxine and alpha-hydroxyisocaproic acid (HICA) | PNPO, CYP3A5, CYP8B1 | KDM4E 1424/4885ALDH1A1 871/4885HPGD 17/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.