Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 9/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | CALML3 | P27482 | 1/20 | 0.39 |
| ▸ | SDHA | P31040 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1223520 | 1.00 | KCNH2 (0.40) | KCNH2MAOASLC2A1MAOBLMNA | |
| SCHEMBL1223523 | 1.00 | KCNH2 (0.40) | KCNH2MAOASLC2A1MAOBLMNA | |
| SCHEMBL1223576 | 1.00 | KCNH2 (0.40) | KCNH2MAOASLC2A1MAOBLMNA | |
| SCHEMBL1224595 | 0.96 | KCNH2 (0.42) | KCNH2MAOAMAOBLMNAPTGS1 | |
| SCHEMBL1224591 | 0.96 | KCNH2 (0.42) | KCNH2MAOAMAOBLMNAPTGS1 | |
| SCHEMBL1222712 | 0.94 | MAOA (0.40) | KCNH2MAOAMAOBLMNAPTGS1 | |
| SCHEMBL1222717 | 0.94 | MAOA (0.40) | KCNH2MAOAMAOBLMNAPTGS1 | |
| SCHEMBL1223708 | 0.88 | KCNH2 (0.46) | KCNH2SLC2A1 | |
| SCHEMBL1222576 | 0.88 | KCNH2 (0.46) | KCNH2SLC2A1 | |
| SCHEMBL1222573 | 0.88 | KCNH2 (0.46) | KCNH2SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2144910-A2 | OXAZOLIDINONE ANTIBIOTICS | Actelion Pharmaceuticals Ltd. (CH) | 2010-01-20 | — | — | EP | disclosed |
| WO-2008126034-A2 | OXAZOLIDINONE ANTIBIOTICS | ACTELION PHARMACEUTICALS LTD (CH) | 2008-10-23 | — | — | WO | disclosed |