Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2005583 | 1.00 | P2RX7 (0.83) | P2RX7IL1B | |
| SCHEMBL2005585 | 1.00 | P2RX7 (0.83) | P2RX7IL1B | |
| SCHEMBL2010217 | 0.96 | P2RX7 (0.85) | P2RX7 | |
| SCHEMBL2007598 | 0.96 | P2RX7 (0.85) | P2RX7 | |
| SCHEMBL2010222 | 0.96 | P2RX7 (0.85) | P2RX7 | |
| SCHEMBL2007601 | 0.96 | P2RX7 (0.85) | P2RX7 | |
| SCHEMBL17323979 | 0.94 | P2RX7 (0.84) | P2RX7IL1B | |
| SCHEMBL17323933 | 0.94 | P2RX7 (0.84) | P2RX7IL1B | |
| SCHEMBL17323934 | 0.91 | P2RX7 (1.00) | P2RX7IL1B | |
| SCHEMBL17324059 | 0.91 | P2RX7 (1.00) | P2RX7IL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139879-A1 | QUINOLINE DERIVATIVES FOR THE TREATMENT OF INFLAMMATORY DISEASES | AstraZeneca AB (SE) | 2010-01-06 | — | — | EP | claimed |
| WO-2008114002-A1 | QUINOLINE DERIVATIVES FOR THE TREATMENT OF INFLAMMATORY DISEASES | ASTRAZENECA AB (SE) | 2008-09-25 | — | — | WO | claimed |