SCHEMBL3670122

SCHEMBL3670122

NC(N)Cc1ccc2ccccc2c1Cl

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.48
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
HTR2A P28223 1/20 0.39
HTR2C P28335 1/20 0.39
CYP1A2 P05177 1/20 0.38
ITGB2 P05107 1/20 0.37
ICAM1 P05362 1/20 0.37
ITGAL P20701 1/20 0.37
HPRT1 P00492 1/20 0.37
PAX8 Q06710 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5293815 0.80 MAPT (0.51) ALDH1A1TSHRHSD17B10TDP1
SCHEMBL6404480 0.79 CYP2A6 (0.54) CYP2A6ALDH1A1TSHRHSD17B10TDP1
SCHEMBL3670407 0.78 POLB (0.46) CYP2A6ALDH1A1TSHRHSD17B10TDP1
SCHEMBL3668888 0.78 HTR2A (0.42) CYP2A6ALDH1A1TSHRHSD17B10TDP1
SCHEMBL3681421 0.76 CYP1A2 (0.52) ALDH1A1TSHRHSD17B10TDP1CYP1A2
SCHEMBL4453260 0.76 CYP2A6 (0.56) CYP2A6ALDH1A1TSHRHSD17B10TDP1
SCHEMBL12013593 0.76 CYP2A6 (0.56) CYP2A6ALDH1A1TSHRHSD17B10TDP1
SCHEMBL4697244 0.75 CYP2A6 (0.54) CYP2A6ALDH1A1TSHRHSD17B10TDP1
SCHEMBL8895165 0.75 CYP2A6 (0.54) CYP2A6ALDH1A1TSHRHSD17B10TDP1
SCHEMBL6910872 0.75 CYP2A6 (0.54) CYP2A6ALDH1A1TSHRHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1426392-B1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL CO (JP) 2010-02-24 EP disclosed
US-6960640-B2 Composition for optical material MITSUBISHI GAS CHEMICAL CO., LTD. (JP) 2005-11-01 US disclosed
US-20040147708-A1 Composition for optical material MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-07-29 US disclosed
EP-1426392-A1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-06-09 EP disclosed