SCHEMBL3670581

SCHEMBL3670581

CS(=O)(=O)N(SC(Cl)(Cl)Cl)c1ccc(Cl)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 1/20 0.46
CCNB1 P14635 1/20 0.46
CCNA2 P20248 1/20 0.46
CCND1 P24385 1/20 0.46
CDK2 P24941 1/20 0.46
CDK7 P50613 1/20 0.46
CCNH P51946 1/20 0.46
CCNA1 P78396 1/20 0.46
CDK6 Q00534 1/20 0.46
ALDH1A1 P00352 3/20 0.41
KDM4E B2RXH2 2/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
HSD17B10 Q99714 1/20 0.41
PTGS2 P35354 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CA12 O43570 2/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA3 P07451 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27395569 0.84 CDK1 (0.40) CDK1CCNB1CCNA2CCND1CDK2
SCHEMBL11369479 0.83 ALDH1A1 (0.37) CDK1CCNB1CCNA2CCND1CDK2
SCHEMBL11118408 0.83 ALDH1A1 (0.37) CDK1CCNB1CCNA2CCND1CDK2
SCHEMBL32679367 0.83 ALDH1A1 (0.37) CDK1CCNB1CCNA2CCND1CDK2
SCHEMBL3670579 0.81 CDK1 (0.43) CDK1CCNB1CCNA2CCND1CDK2
SCHEMBL11118410 0.78 ALDH1A1 (0.38) CDK1CCNB1CCNA2CCND1CDK2
SCHEMBL30503677 0.76 CDK1 (0.44) CDK1CCNB1CCNA2CCND1CDK2
SCHEMBL11118414 0.72 ALDH1A1 (0.39) ALDH1A1KDM4EHPGDALOX15HSD17B10
SCHEMBL6320855 0.69 ALDH1A1 (0.53) ALDH1A1KDM4EHPGDALOX15HSD17B10
SCHEMBL11370118 0.68 ALDH1A1 (0.38) CDK1CCNB1CCNA2CCND1CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114948963-A Protein kinase inhibitor benzolactam compounds 大冢制药株式会社 2022-08-30 CN claimed
CN-117529551-A Virus-specific immune cells expressing chimeric antigen receptor 贝勒医学院 2024-02-06 CN disclosed
CN-112955008-B Prevention and control method for wheat diseases, wheat seeds and inhibition method for lodging loss of wheat 组合化学工业株式会社 2023-07-14 CN disclosed
EP-3601297-B9 COMPOUNDS THAT INHIBIT MCL-1 PROTEIN AMGEN INC (US) 2023-05-24 EP disclosed
EP-3601297-B1 COMPOUNDS THAT INHIBIT MCL-1 PROTEIN AMGEN INC (US) 2022-10-19 EP disclosed
CN-112105264-B Polymeric dispersants for pesticides 禾大国际股份公开有限公司 2022-08-26 CN disclosed
CN-113853460-A Polyester fiber structure, method for producing same, clothing, and bedding 东丽株式会社 2021-12-28 CN disclosed
EP-2197960-A2 ANTIFOULING COATING Taimeitech Co., Ltd. (JP) 2010-06-23 EP disclosed
WO-2009047955-A2 ANTIFOULING COATING TAIMEITECH CO., LTD. (JP) 2009-04-16 WO disclosed
CN-1089997-C Antimicrobial composition SUGANUMA AKIO (JP) 2002-09-04 CN disclosed
CN-1181185-A Antimicrobial composition AKIO SUGUNUMA (JP) 1998-05-13 CN disclosed
US-4324799-A Fungicidal thioglycolic acid anilides, processes for their manufacture and pesticidal compositions containing them HOECHST AKTIENGESELLSCHAFT (DE) 1982-04-13 US disclosed
EP-0023332-A2 Fungicidal thioglycolic acid anilides, process for their preparation and pesticides containing them HOECHST AKTIENGESELLSCHAFT (DE) 1981-02-04 EP disclosed
US-3974166-A FUNGICIDE CIBA-GEIGY CORPORATION (US) 1976-08-10 US disclosed
US-3932509-A FUNGICIDES, VIRICIDES CIBA-GEIGY CORPORATION (US) 1976-01-13 US disclosed