Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 8/20 | 0.58 |
| ▸ | CPA1 | P15085 | 3/20 | 0.39 |
| ▸ | CPB1 | P15086 | 1/20 | 0.39 |
| ▸ | CPA3 | P15088 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31158240 | 0.86 | FOLH1 (0.48) | FOLH1CPB2TDP1 | |
| SCHEMBL31158244 | 0.86 | FOLH1 (0.48) | FOLH1CPB2TDP1 | |
| SCHEMBL7762277 | 0.85 | CHRM1 (0.48) | FOLH1CPA1CPB2TDP1CHRM1 | |
| SCHEMBL6441158 | 0.80 | FOLH1 (0.56) | FOLH1CPA1CPB1CPA3CPB2 | |
| SCHEMBL21802279 | 0.80 | FOLH1 (0.75) | FOLH1CPA1CPB1CPA3CPB2 | |
| SCHEMBL164322 | 0.80 | FOLH1 (0.75) | FOLH1CPA1CPB1CPA3CPB2 | |
| SCHEMBL31075345 | 0.79 | SLC1A1 (0.41) | FOLH1CPA1CPB2TDP1CHRM1 | |
| SCHEMBL12133771 | 0.76 | FOLH1 (0.56) | FOLH1CPA1CPB1CPA3CPB2 | |
| SCHEMBL3904508 | 0.76 | CHRM1 (0.70) | TDP1SMN1; SMN2CHRM1AKR1A1CHRM3 | |
| SCHEMBL29217 | 0.75 | FOLH1 (0.68) | FOLH1CPA1CPB1CPA3CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4323415-A1 | PREPOLYMERIZED CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2024-02-21 | — | — | EP | disclosed |
| EP-3810661-A1 | POLYPROPYLENE COMPOSITION AND MOLDED ARTICLE | Basell Poliolefine Italia S.r.l. (IT) | 2021-04-28 | — | — | EP | disclosed |
| EP-3765534-A1 | POLYPROPYLENE COMPOSITION AND MOLDED ARTICLE | Basell Poliolefine Italia S.r.l. (IT) | 2021-01-20 | — | — | EP | disclosed |
| EP-3765566-A1 | POLYPROPYLENE COMPOSITION AND MOLDED ARTICLE | Basell Poliolefine Italia S.r.l. (IT) | 2021-01-20 | — | — | EP | disclosed |
| WO-2020080555-A1 | POLYPROPYLENE COMPOSITION AND MOLDED ARTICLE | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2020-04-23 | — | — | WO | disclosed |
| WO-2019177180-A1 | POLYPROPYLENE COMPOSITION AND MOLDED ARTICLE | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2019-09-19 | — | — | WO | disclosed |
| WO-2019177179-A1 | POLYPROPYLENE COMPOSITION AND MOLDED ARTICLE | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2019-09-19 | — | — | WO | disclosed |
| CN-104703976-B | Double (fluoroalkyls) 1,4 benzodiazepine * assimilation compound is used as NOTCH inhibitor | 百时美施贵宝公司 | 2017-03-08 | — | — | CN | disclosed |
| US-20150284342-A1 | BIS(FLUOROALKYL)-1,4-BENZODIAZEPINONE COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2015-10-08 | — | — | US | disclosed |
| EP-2542592-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.R.L. (IT) | 2013-01-09 | — | — | EP | disclosed |
| EP-2201049-A2 | PROCESS FOR THE PREPARATION OF HIGH FLUIDITY PROPYLENE POLYMERS | Basell Poliolefine Italia S.r.l. (IT) | 2010-06-30 | — | — | EP | disclosed |
| WO-2009050045-A2 | PROCESS FOR THE PREPARATION OF HIGH FLUIDITY PROPYLENE POLYMERS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2009-04-23 | — | — | WO | disclosed |
| EP-1539838-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.P.A. (IT) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004024785-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2004-03-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150284342-A1 | BIS(FLUOROALKYL)-1,4-BENZODIAZEPINONE COMPOUNDS | CNR1, CNR2, NR1I3 | FOLH1 1429/4885CPA1 2882/4885CPB1 3035/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.