Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.72 |
| ▸ | F7 | P08709 | 4/20 | 0.72 |
| ▸ | F3 | P13726 | 4/20 | 0.72 |
| ▸ | PPARD | Q03181 | 4/20 | 0.72 |
| ▸ | PPARA | Q07869 | 4/20 | 0.72 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.72 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.72 |
| ▸ | ESR1 | P03372 | 1/20 | 0.72 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.72 |
| ▸ | CASP6 | P55212 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.70 |
| ▸ | FABP3 | P05413 | 3/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.70 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.70 |
| ▸ | FABP4 | P15090 | 2/20 | 0.70 |
| ▸ | HPGD | P15428 | 2/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15908475 | 1.00 | PPARG (0.72) | PPARGF7F3PPARDPPARA | |
| SCHEMBL10740192 | 1.00 | PPARG (0.72) | PPARGF7F3PPARDPPARA | |
| SCHEMBL10740199 | 1.00 | PPARG (0.72) | PPARGF7F3PPARDPPARA | |
| SCHEMBL12629207 | 1.00 | PPARG (0.72) | PPARGF7F3PPARDPPARA | |
| SCHEMBL3670919 | 1.00 | PPARG (0.72) | PPARGF7F3PPARDPPARA | |
| SCHEMBL15908476 | 0.98 | ALDH1A1 (0.73) | PPARGF7F3PPARDPPARA | |
| SCHEMBL15908489 | 0.98 | ALDH1A1 (0.73) | PPARGF7F3PPARDPPARA | |
| SCHEMBL21302754 | 0.98 | ALDH1A1 (0.73) | PPARGF7F3PPARDPPARA | |
| SCHEMBL11893268 | 0.98 | ALDH1A1 (0.73) | PPARGF7F3PPARDPPARA | |
| SCHEMBL3414485 | 0.98 | ALDH1A1 (0.73) | PPARGF7F3PPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7795302-B2 | Use of compositions for treating rosacea | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2010-09-14 | — | — | US | disclosed |
| US-20080070874-A1 | using retinoid or tetracycline as bactericide, benzoyl peroxide as metalloproteinases (MMPs) and neutrophil elastase inhibitors; antiscarring agents; reduction in procollagen biosynthesis | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2008-03-20 | — | — | US | disclosed |
| US-7268148-B2 | Compositions and methods for use against acne-induced inflammation and dermal matrix-degrading enzymes | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2007-09-11 | — | — | US | disclosed |
| US-7078048-B2 | Method and compositions for treating rosacea | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2006-07-18 | — | — | US | disclosed |
| US-20060078582-A1 | Use of compositions for treating rosacea | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2006-04-13 | — | — | US | disclosed |
| EP-1385496-A4 | USE OF COMPOSITIONS FOR TREATING ROSACEA | UNIV MICHIGAN (US) | 2006-03-29 | — | — | EP | disclosed |
| US-20060009494-A1 | Compositions and methods for use against acne-induced inflammation and dermal matrix-degrading enzymes | VOORHEES JOHN J | 2006-01-12 | — | — | US | disclosed |
| US-20050277695-A1 | Compositions and methods for use against acne-induced inflammation and dermal matrix-degrading enzymes | VOORHEES JOHN J | 2005-12-15 | — | — | US | disclosed |
| US-20040235950-A1 | Compositions and methods for use against acne-induced inflammation and dermal matrix-degrading enzymes | REGENTS OF THE UNIVERSITY OF MICHIGAN, THE | 2004-11-25 | — | — | US | disclosed |
| EP-1385496-A2 | USE OF COMPOSITIONS FOR TREATING ROSACEA | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2004-02-04 | — | — | EP | disclosed |
| EP-1284721-A2 | COMPOSITIONS AND METHODS FOR USE AGAINST ACNE-INDUCED INFLAMMATION AND DERMAL MATRIX-DEGRADING ENZYMES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2003-02-26 | — | — | EP | disclosed |
| US-20020183399-A1 | Method and compositions for treating rosacea | REGENTS OF THE UNIVERSITY OF MICHIGAN, THE | 2002-12-05 | — | — | US | disclosed |
| WO-2002089743-A2 | USE OF COMPOSITIONS FOR TREATING ROSACEA | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2002-11-14 | — | — | WO | disclosed |
| WO-2001089502-A2 | COMPOSITIONS AND METHODS FOR USE AGAINST ACNE-INDUCED INFLAMMATION AND DERMAL MATRIX-DEGRADING ENZYMES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2001-11-29 | — | — | WO | disclosed |