SCHEMBL3671149

SCHEMBL3671149

Cc1ccc(N)c(N)c1Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 8/20 0.46
CD44 P16070 2/20 0.44
ALDH1A1 P00352 7/20 0.39
TDP1 Q9NUW8 7/20 0.39
TSHR P16473 4/20 0.39
POLB P06746 2/20 0.39
CASP1 P29466 1/20 0.39
MAPT P10636 3/20 0.35
GAA P10253 1/20 0.35
ALOX15 P16050 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
THRB P10828 2/20 0.35
TP53 P04637 1/20 0.35
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
APEX1 P27695 1/20 0.33
RECQL P46063 1/20 0.33
RAB9A P51151 1/20 0.33
BLM P54132 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31569267 1.00 CYP3A4 (0.46) CYP3A4CD44ALDH1A1TDP1TSHR
SCHEMBL3884369 0.83 CYP3A4 (0.50) CYP3A4CD44ALDH1A1TDP1TSHR
SCHEMBL13655098 0.83 POLB (0.48) CYP3A4CD44ALDH1A1TDP1TSHR
SCHEMBL1638904 0.79 CYP3A4 (0.46) CYP3A4CD44ALDH1A1TDP1TSHR
SCHEMBL28678653 0.79 CYP3A4 (0.46) CYP3A4CD44ALDH1A1TDP1TSHR
SCHEMBL767710 0.79 CYP3A4 (0.46) CYP3A4CD44ALDH1A1TDP1TSHR
SCHEMBL19472050 0.75 CYP3A4 (0.38) CYP3A4CD44ALDH1A1TDP1TSHR
SCHEMBL18697999 0.75 CYP3A4 (0.43) CYP3A4CD44ALDH1A1TDP1TSHR
SCHEMBL3790991 0.75 ALDH1A1 (0.47) CYP3A4ALDH1A1TDP1TSHRPOLB
SCHEMBL6582691 0.75 CYP3A4 (0.43) CYP3A4CD44ALDH1A1TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025101780-A1 PHARMACOLOGICAL CORRECTORS OF RHODOPSIN AND USES THEREOF OCTANT, INC. (US) 2025-05-15 WO disclosed
US-9873701-B2 Heterocyclic compounds and their uses AMGEN INC. (US) 2018-01-23 US disclosed
EP-1426392-B1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL CO (JP) 2010-02-24 EP disclosed
EP-1089982-B1 METHODS OF INHIBITING CORROSION USING ISOMERS OF CHLORO-METHYLBENZOTRIAZOLE BETZDEARBORN INC (US) 2006-08-30 EP disclosed
US-6960640-B2 Composition for optical material MITSUBISHI GAS CHEMICAL CO., LTD. (JP) 2005-11-01 US disclosed
EP-1089982-A4 METHODS OF INHIBITING CORROSION USING ISOMERS OF CHLORO-METHYLBENZOTRIAZOLE BETZDEARBORN INC (US) 2005-04-06 EP disclosed
CN-1184210-C Methods of inhibiting corrosion using isomers of chloro-methylbenzotrazole BETZDEARBORN INC (US) 2005-01-12 CN disclosed
US-20040147708-A1 Composition for optical material MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-07-29 US disclosed
EP-1426392-A1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-06-09 EP disclosed
EP-1089982-A1 METHODS OF INHIBITING CORROSION USING ISOMERS OF CHLORO-METHYLBENZOTRIAZOLE BetzDearborn Inc (US) 2001-04-11 EP disclosed
WO-1999067222-A1 METHODS OF INHIBITING CORROSION USING ISOMERS OF CHLORO-METHYLBENZOTRIAZOLE BETZDEARBORN INC. (US) 1999-12-29 WO disclosed
US-5968408-A ODORLESS BETZDEARBORN INC. (US) 1999-10-19 US disclosed
EP-0336391-B1 Reversibly color-changeable materials TEIJIN LTD (JP) 1994-01-26 EP disclosed
US-5068062-A Crosslinked resin containing 4,4*-diaminodiphenylmethane units with the amine quaternized and an electrolytic material TEIJIN LIMITED (JP) 1991-11-26 US disclosed
EP-0336391-A2 Reversibly color-changeable materials TEIJIN LIMITED (JP) 1989-10-11 EP disclosed