SCHEMBL3671286

SCHEMBL3671286

O=C(Nc1ccccn1)C1CC1

nearest known ligand 0.65

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.65
NPC1 O15118 5/20 0.63
RAB9A P51151 5/20 0.63
PKM P14618 2/20 0.63
ALDH1A1 P00352 1/20 0.62
TP53 P04637 1/20 0.62
ACVRL1 P37023 1/20 0.60
GAA P10253 1/20 0.59
GSK3B P49841 1/20 0.57
LMNA P02545 2/20 0.56
TSHR P16473 1/20 0.56
GRM1 Q13255 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30355896 1.00 HPGD (0.65) HPGDNPC1RAB9APKMALDH1A1
SCHEMBL1515418 0.93 RAB9A (0.60) HPGDNPC1RAB9APKMALDH1A1
SCHEMBL27488421 0.93 RAB9A (0.63) HPGDNPC1RAB9APKMALDH1A1
SCHEMBL10352433 0.92 RAB9A (0.66) HPGDNPC1RAB9APKMALDH1A1
SCHEMBL5139794 0.91 RAB9A (0.65) HPGDNPC1RAB9APKMALDH1A1
Hydrochloric Acid SCHEMBL27440821 0.90 RAB9A (0.64) HPGDNPC1RAB9APKMALDH1A1
SCHEMBL2475102 0.89 RAB9A (0.56) HPGDNPC1RAB9APKMALDH1A1
SCHEMBL1554009 0.88 RAB9A (0.53) HPGDNPC1RAB9APKMALDH1A1
SCHEMBL10352434 0.88 RAB9A (0.59) HPGDNPC1RAB9APKMALDH1A1
SCHEMBL1554007 0.88 RAB9A (0.53) HPGDNPC1RAB9APKMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121153706-B Application of formamide compound in prevention and treatment of ralstonia solanacearum 云南大学 2026-03-20 CN disclosed
CN-121153706-A Application of formamide compound in prevention and treatment of ralstonia solanacearum 云南大学 2025-12-19 CN disclosed
CN-111892592-B JAK kinase inhibitors and uses thereof 江苏柯菲平医药股份有限公司 2023-09-19 CN disclosed
CN-115066425-B Application of JAK inhibitor in preparation of medicines for treating JAK kinase related diseases 珠海联邦制药股份有限公司 2023-06-23 CN disclosed
CN-115066425-A Application of JAK inhibitor in preparation of medicine for treating JAK kinase related diseases 珠海联邦制药股份有限公司 2022-09-16 CN disclosed
CN-112739696-B [1,2,4] triazolo [1,5-a ] pyridines as JAK inhibitors and application thereof 珠海联邦制药股份有限公司 2022-08-02 CN disclosed
CN-114075189-A Five-membered heterocyclic acene ring compound and preparation method and medical application thereof 南京柯菲平盛辉制药有限公司 2022-02-22 CN disclosed
EP-2789606-B1 Modulators of CFTR VERTEX PHARMA (US) 2017-11-15 EP disclosed
EP-2162445-A1 HETEROBICYCLIC COMPOUNDS AS KINASE INHIBITORS Takeda Pharmaceutical Company Limited (JP) 2010-03-17 EP disclosed
WO-2009136663-A1 FUSED HETEROCYCLIC DERIVATIVES AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-11-12 WO disclosed
CN-87103160-A Fungicidal pyridyl cyclopropane carboxamides 1988-04-27 CN disclosed
CN-87103160-A Fungicidal pyridyl cyclopropane carboxamides 1988-04-27 CN disclosed
CN-87103191-A FUNGICIDAL PYRIDYL CYCLOPROPANE CARBOXAMIDES 1987-11-25 CN disclosed
CN-87103191-A FUNGICIDAL PYRIDYL CYCLOPROPANE CARBOXAMIDES 1987-11-25 CN disclosed
EP-0243971-A2 Fungicidal pyridyl cyclopropane carboxamides STAUFFER CHEMICAL COMPANY (US) 1987-11-04 EP disclosed
EP-0243971-A2 Fungicidal pyridyl cyclopropane carboxamides STAUFFER CHEMICAL COMPANY (US) 1987-11-04 EP disclosed
EP-0243972-A2 Fungicidal pyridyl cyclopropane carboximides STAUFFER CHEMICAL COMPANY (US) 1987-11-04 EP disclosed
EP-0243972-A2 Fungicidal pyridyl cyclopropane carboximides STAUFFER CHEMICAL COMPANY (US) 1987-11-04 EP disclosed
EP-0243971-A2 Fungicidal pyridyl cyclopropane carboxamides STAUFFER CHEMICAL COMPANY (US) 1987-11-04 EP disclosed
US-4149872-A N-pyridinyl urea and cyclopropanecarboxamide herbicides SHELL OIL COMPANY (US) 1979-04-17 US disclosed