SCHEMBL3671335

SCHEMBL3671335

Cc1ccc(C(Br)(CN)CN)cc1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.46
KIF11 P52732 7/20 0.42
TAAR1 Q96RJ0 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2A6 P11509 1/20 0.41
ACHE P22303 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA5A P35218 1/20 0.39
CA9 Q16790 1/20 0.39
ALDH1A1 P00352 1/20 0.38
NPC1 O15118 1/20 0.35
MAPT P10636 1/20 0.35
RAB9A P51151 1/20 0.35
AGXT P21549 2/20 0.34
IDO1 P14902 1/20 0.33
CYP19A1 P11511 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6060758 0.77 TSHR (0.48) TSHRKIF11TAAR1CYP1A2CYP2A6
SCHEMBL1972845 0.77 TSHR (0.48) TSHRKIF11ACHETDP1CA1
SCHEMBL8350486 0.75 TAAR1 (0.62) TSHRKIF11TAAR1CYP1A2CYP2A6
SCHEMBL3673509 0.74 TAAR1 (0.54) TSHRKIF11TAAR1CYP2A6ALDH1A1
SCHEMBL3671013 0.73 CA2 (0.47) TSHRKIF11TAAR1CYP1A2CYP2A6
Hydrochloric Acid SCHEMBL8508449 0.73 TAAR1 (0.60) TSHRKIF11TAAR1CYP1A2CYP2A6
SCHEMBL3676012 0.73 TSHR (0.44) TSHRKIF11TAAR1CYP1A2CYP2A6
SCHEMBL8257138 0.73 CA1 (0.47) TSHRKIF11TAAR1CYP1A2CYP2A6
SCHEMBL12015994 0.71 TSHR (0.48) TSHRKIF11TAAR1CYP1A2CYP2A6
SCHEMBL3668818 0.70 TSHR (0.52) TSHRKIF11TAAR1CYP1A2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1426392-B1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL CO (JP) 2010-02-24 EP disclosed
US-6960640-B2 Composition for optical material MITSUBISHI GAS CHEMICAL CO., LTD. (JP) 2005-11-01 US disclosed
US-20040147708-A1 Composition for optical material MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-07-29 US disclosed
EP-1426392-A1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-06-09 EP disclosed