SCHEMBL367143

SCHEMBL367143

In1cccn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL204583 0.67
SCHEMBL9464929 0.65 NOS1 (0.38)
SCHEMBL27838219 0.61
SCHEMBL2475851 0.61
SCHEMBL27958769 0.61
SCHEMBL25566062 0.61
SCHEMBL7054975 0.61
SCHEMBL3506516 0.61
SCHEMBL10597138 0.61
SCHEMBL7529827 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 644 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118847062-A 4-Iodopyrazole-loaded UiO-67 material and preparation method and application thereof 中南大学 2024-10-29 CN claimed
US-11612614-B2 Isomorphs of Remdesivir and methods for synthesis of same Anzalp Pharmasolutions Pvt. Ltd. (IN) 2023-03-28 US claimed
US-20210228605-A1 ISOMORPHS OF REMDESIVIR AND METHODS FOR SYNTHESIS OF SAME Anzalp Pharmasolutions Pvt. Ltd. (IN) 2021-07-29 US claimed
US-20210161927-A1 ISOMORPHS OF REMDESIVIR AND METHODS FOR SYNTHESIS OF SAME Anzalp Pharmasolutions Pvt. Ltd. (IN) 2021-06-03 US claimed
CN-105777755-A Preparation method for Imbruvica intermediate, i.e., 3-iodo-1H-pyrazolo[3,4-D]pyrimidin-4-amine 常州百敖威生物科技有限公司 2016-07-20 CN claimed
EP-0973767-A1 INDAZOLES OF CYCLIC UREAS USEFUL AS HIV PROTEASE INHIBITORS Dupont Pharmaceuticals Company (US) 2000-01-26 EP claimed
US-5985867-A TREATING HIV INFECTION DUPONT PHARMACEUTICALS COMPANY (US) 1999-11-16 US claimed
WO-1998043969-A1 INDAZOLES OF CYCLIC UREAS USEFUL AS HIV PROTEASE INHIBITORS DUPONT PHARMACEUTICALS COMPANY (US) 1998-10-08 WO claimed
CN-116854630-B Methods and intermediates for preparing therapeutic compounds useful in the treatment of retroviral infections 吉利德科学公司 2026-05-19 CN disclosed
WO-2026101724-A1 AMINO PYRIMIDINE AND AMINO TRIAZINE ANALOGS FOR TREATING CANCER NEREID THERAPEUTICS INCORPORATED (US) 2026-05-15 WO disclosed
EP-4739397-A1 FUSED PYRAZOLE DERIVATIVES AS USP1 INHIBITORS Exelixis, Inc. (US) 2026-05-13 EP disclosed
US-12479816-B2 20-HETE formation inhibitors University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2025-11-25 US disclosed
US-20250340559-A1 PROCESSES FOR PREPARING JAK INHIBITORS AND RELATED INTERMEDIATE COMPOUNDS INCYTE HOLDINGS CORP (US) 2025-11-06 US disclosed
EP-3600294-B1 TRI-SUBSTITUTED IMIDAZOLES FOR THE INHIBITION OF TGF BETA AND METHODS OF TREATMENT CLAVIUS PHARMACEUTICALS LLC (US) 2025-09-03 EP disclosed
EP-0973767-A1 INDAZOLES OF CYCLIC UREAS USEFUL AS HIV PROTEASE INHIBITORS Dupont Pharmaceuticals Company (US) 2000-01-26 EP disclosed
US-5985867-A TREATING HIV INFECTION DUPONT PHARMACEUTICALS COMPANY (US) 1999-11-16 US disclosed
EP-0944581-A1 PROCESS OF PREPARING SUBSTITUTED ACRYLAMIDES ELI LILLY AND COMPANY (US) 1999-09-29 EP disclosed
US-5917038-A REACTING PROPIOLAMIDE WITH ACTIVATED AROMATIC RING IN THE PRESENCE OF A PALLADIUM CATALYST ELI LILLY AND COMPANY (US) 1999-06-29 US disclosed
WO-1998043969-A1 INDAZOLES OF CYCLIC UREAS USEFUL AS HIV PROTEASE INHIBITORS DUPONT PHARMACEUTICALS COMPANY (US) 1998-10-08 WO disclosed
WO-1998022429-A1 PROCESS OF PREPARING SUBSTITUTED ACRYLAMIDES ELI LILLY AND COMPANY (US) 1998-05-28 WO disclosed