Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.41 |
| ▸ | PPARD | Q03181 | 5/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3777818 | 0.93 | PTGDR2 (0.44) | PTGDR2PPARDTSHRTDP1RORC | |
| SCHEMBL3779640 | 0.92 | PTGDR2 (0.45) | PTGDR2PPARDTSHRTDP1RORC | |
| SCHEMBL533998 | 0.89 | PTGDR2 (0.40) | PTGDR2PPARDAKR1B1TSHRTDP1 | |
| SCHEMBL2574695 | 0.89 | PTGDR2 (0.33) | PTGDR2TSHR | |
| SCHEMBL3786033 | 0.89 | PTGDR2 (0.40) | PTGDR2RORC | |
| SCHEMBL2572541 | 0.88 | PTGDR2 (0.39) | PTGDR2PPARDTSHRTDP1RORC | |
| SCHEMBL10331941 | 0.87 | PTGDR2 (0.39) | PTGDR2PPARDTSHRTDP1RORC | |
| SCHEMBL3724274 | 0.86 | PTGDR2 (0.39) | PTGDR2PPARD | |
| SCHEMBL2573522 | 0.86 | PTGDR2 (0.38) | PTGDR2PPARD | |
| SCHEMBL3785469 | 0.85 | PTGDR2 (0.51) | PTGDR2PPARDTSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139881-A1 | QUINOLINES AND THEIR THERAPEUTIC USE | Argenta Oral Therapeutics Limited (GB) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008122784-A1 | QUINOLINES AND THEIR THERAPEUTIC USE | ARGENTA DISCOVERY LIMITED (GB) | 2008-10-16 | — | — | WO | disclosed |