SCHEMBL3779640

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3777818	0.94	PTGDR2 (0.44)	PTGDR2PPARDTSHRTDP1RORC
	SCHEMBL3781764	0.93	PTGDR2 (0.40)	PTGDR2PLA2G2APPARDFFAR1TSHR
	SCHEMBL3671435	0.92	PTGDR2 (0.41)	PTGDR2PPARDTSHRTDP1RORC
	SCHEMBL3772529	0.91	ALDH1A1 (0.38)	PTGDR2PLA2G2A
	SCHEMBL3780664	0.91	PTGDR2 (0.54)	PTGDR2PLA2G2APPARDFFAR1PTGDR
	SCHEMBL533998	0.90	PTGDR2 (0.40)	PTGDR2PPARDTSHRTDP1RORC
	SCHEMBL3786033	0.89	PTGDR2 (0.40)	PTGDR2PTGDRRORC
	SCHEMBL2572541	0.89	PTGDR2 (0.39)	PTGDR2PPARDTSHRTDP1RORC
	SCHEMBL3785469	0.88	PTGDR2 (0.51)	PTGDR2PPARDTSHRTDP1
	SCHEMBL10331941	0.88	PTGDR2 (0.39)	PTGDR2PPARDTSHRTDP1RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.