SCHEMBL3671577

SCHEMBL3671577

C=CCCCCCCc1ccc(C=C)cc1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
USP2 O75604 1/20 0.44
HPGD P15428 1/20 0.44
HDAC1 Q13547 2/20 0.44
HDAC4 P56524 1/20 0.43
THRA P10827 5/20 0.38
THRB P10828 5/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
TSHR P16473 1/20 0.37
LMNA P02545 1/20 0.36
TRPV1 Q8NER1 1/20 0.36
SPHK2 Q9NRA0 3/20 0.35
SPHK1 Q9NYA1 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3670690 0.92 ALDH1A1 (0.48) ALDH1A1TDP1USP2HPGDHDAC1
SCHEMBL1140602 0.89 ALDH1A1 (0.55) ALDH1A1TDP1THRATHRBMEN1
SCHEMBL594419 0.89 ALDH1A1 (0.55) ALDH1A1TDP1THRATHRBMEN1
SCHEMBL1140808 0.89 ALDH1A1 (0.55) ALDH1A1TDP1THRATHRBMEN1
SCHEMBL11336193 0.89 TDP1 (0.52) ALDH1A1TDP1USP2HPGDHDAC1
SCHEMBL3797757 0.89 ALDH1A1 (0.55) ALDH1A1TDP1THRATHRBMEN1
SCHEMBL6278400 0.89 ALDH1A1 (0.55) ALDH1A1TDP1THRATHRBMEN1
SCHEMBL12989712 0.89 TDP1 (0.52) ALDH1A1TDP1USP2HPGDHDAC1
SCHEMBL6285095 0.89 ALDH1A1 (0.55) ALDH1A1TDP1THRATHRBMEN1
SCHEMBL11328438 0.87 TDP1 (0.48) ALDH1A1TDP1USP2HPGDHDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016108715-A1 DILITHIUM INITIATOR FOR ANIONIC POLYMERIZATION PUBLIC JOINT STOCK COMPANY "SIBUR HOLDING" (RU) 2016-07-07 WO claimed
US-5418276-A Styrene copolymer, syndiotactic, heat resistance, chemical resistance IDEMITSU KOSAN CO., LTD. (JP) 1995-05-23 US claimed
US-5362814-A Styrene polymers with olefin monomers and diolefin monomers for impact strength in molding materials IDEMITSU KOSAN CO., LTD. (JP) 1994-11-08 US claimed
WO-2016108715-A1 DILITHIUM INITIATOR FOR ANIONIC POLYMERIZATION PUBLIC JOINT STOCK COMPANY "SIBUR HOLDING" (RU) 2016-07-07 WO disclosed
US-8461271-B2 Graft copolymer, thermoplastic resin composition comprising the graft copolymer, and those production method IDEMITSU KOSAN CO., LTD. (JP) 2013-06-11 US disclosed
EP-1408080-B1 POLYOLEFIN RESIN COMPOSITION IDEMITSU KOSAN CO (JP) 2012-12-26 EP disclosed
US-20100076146-A1 GRAFT COPOLYMER, THERMOPLASTIC RESIN COMPOSITION COMPRISING THE GRAFT COPOLYMER, AND THOSE PRODUCTION METHOD IDEMITSU KOSAN CO., LTD. (JP) 2010-03-25 US disclosed
US-7531605-B2 Process for producing polyolefin resin composition and polypropylene composition IDEMITSU KOSAN CO., LTD. (JP) 2009-05-12 US disclosed
EP-1375538-B1 PROCESS FOR PRODUCING POLYOLEFIN RESIN COMPOSITION AND POLYPROPYLENE COMPOSITION IDEMITSU KOSAN CO (JP) 2008-01-09 EP disclosed
US-7193013-B2 Polyolefin resin composition IDEMITSU KOSAN CO. LTD. (JP) 2007-03-20 US disclosed
US-7189788-B2 Polyolefin resin composition IDEMITSU KOSAN CO. LTD. (JP) 2007-03-13 US disclosed
EP-0686649-B1 PROPYLENE BLOCK COPOLYMER, PROCESS FOR PRODUCING THE SAME, AND MODIFIED COPOLYMER PRODUCED THEREFROM IDEMITSU KOSAN CO (JP) 2000-08-02 EP disclosed
US-5670580-A POLYMERS FOR ANTISTATIC AGENTS, ADHESIVES AND FIREPROOFING IDEMITSU KOSAN CO., LTD. (JP) 1997-09-23 US disclosed
EP-0559108-B1 Graft copolymer, process for production thereof and resin composition containing same IDEMITSU KOSAN CO (JP) 1997-05-28 EP disclosed
US-5608009-A OLEFIN-DIOLEFIN GRAFT POLYMER IDEMITSU KOSAN CO., LTD. (JP) 1997-03-04 US disclosed
EP-0686649-A1 PROPYLENE BLOCK COPOLYMER, PROCESS FOR PRODUCING THE SAME, AND MODIFIED COPOLYMER PRODUCED THEREFROM IDEMITSU KOSAN COMPANY LIMITED (JP) 1995-12-13 EP disclosed
EP-0667359-A1 OLEFIN COPOLYMERS AND PROCESS FOR PRODUCING THE SAME IDEMITSU KOSAN COMPANY LIMITED (JP) 1995-08-16 EP disclosed
US-5418276-A Styrene copolymer, syndiotactic, heat resistance, chemical resistance IDEMITSU KOSAN CO., LTD. (JP) 1995-05-23 US disclosed
US-5362814-A Styrene polymers with olefin monomers and diolefin monomers for impact strength in molding materials IDEMITSU KOSAN CO., LTD. (JP) 1994-11-08 US disclosed
EP-0559108-A1 Graft copolymer, process for production thereof and resin composition containing same IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-09-08 EP disclosed