Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3235519 | 0.81 | KRAS (0.45) | CYP1A2CYP3A4CYP2C19MEN1KMT2A | |
| SCHEMBL13494711 | 0.81 | CYP1A2 (0.44) | CYP1A2CYP3A4CYP2C19MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3582811 | 0.80 | SMN1; SMN2 (0.47) | CYP1A2CYP3A4CYP2C19MEN1KMT2A | |
| SCHEMBL3262736 | 0.79 | CYP1A2 (0.45) | CYP1A2CYP3A4CYP2C19MEN1KMT2A | |
| SCHEMBL3639386 | 0.76 | CYP1A2 (0.57) | CYP1A2CYP3A4CYP2C19MEN1KMT2A | |
| SCHEMBL4022728 | 0.72 | MEN1 (0.49) | CYP1A2CYP3A4CYP2C19MEN1KMT2A | |
| SCHEMBL3638377 | 0.70 | KRAS (0.51) | CYP1A2CYP3A4CYP2C19MEN1KMT2A | |
| SCHEMBL13980595 | 0.70 | MEN1 (0.43) | CYP1A2CYP3A4CYP2C19MEN1KMT2A | |
| SCHEMBL13980354 | 0.70 | CYP1A2 (0.43) | CYP1A2CYP3A4CYP2C19MEN1KMT2A | |
| SCHEMBL13980155 | 0.70 | KMT2A (0.50) | CYP1A2CYP3A4CYP2C19MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2167077-A2 | ARYL/HETARYLAMIDES AS MODULATORS OF THE EP2 RECEPTOR | Bayer Schering Pharma Aktiengesellschaft (DE) | 2010-03-31 | — | — | EP | disclosed |