Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4560753 | 0.84 | CYP1A2 (0.46) | CYP1A2CYP3A4CYP2C19KDM4EMAPT | |
| SCHEMBL3234804 | 0.80 | CYP1A2 (0.43) | CYP1A2CYP3A4CYP2C19MEN1KMT2A | |
| SCHEMBL3671627 | 0.79 | CYP1A2 (0.45) | CYP1A2CYP3A4CYP2C19KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL3622627 | 0.79 | SMN1; SMN2 (0.43) | CYP1A2CYP3A4CYP2C19MAPTMEN1 | |
| SCHEMBL3381299 | 0.76 | CYP1A2 (0.57) | CYP1A2CYP3A4CYP2C19KDM4EMAPT | |
| SCHEMBL6446157 | 0.68 | CYP1A2 (0.61) | CYP1A2CYP3A4CYP2C19KDM4EMAPT | |
| SCHEMBL3262045 | 0.64 | MAPT (0.61) | KDM4EMAPTMEN1GAAKMT2A | |
| SCHEMBL4560886 | 0.63 | CYP1A2 (0.56) | CYP1A2CYP3A4CYP2C19KDM4EMAPT | |
| SCHEMBL29926630 | 0.62 | CCNB2 (0.33) | KDM4EMAPTMEN1KMT2A | |
| SCHEMBL4744827 | 0.61 | CYP1A2 (0.73) | CYP1A2CYP3A4CYP2C19KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010012397-A1 | N-(INDOL-3-YLALKYL)(HETERO)ARYLAMIDE DERIVATIVES AS MODULATORS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-02-04 | — | — | WO | claimed |