Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1725810 | 0.84 | BTK (0.59) | BTK | |
| SCHEMBL3205568 | 0.83 | BTK (0.78) | BTK | |
| SCHEMBL3220037 | 0.83 | BTK (0.77) | BTK | |
| SCHEMBL18199140 | 0.82 | BTK (0.56) | BTK | |
| SCHEMBL1576736 | 0.81 | BTK (0.62) | BTK | |
| SCHEMBL1577261 | 0.81 | BTK (0.61) | BTK | |
| SCHEMBL3674873 | 0.80 | BTK (0.58) | BTK | |
| SCHEMBL3207931 | 0.78 | BTK (0.67) | BTK | |
| SCHEMBL17645813 | 0.78 | BTK (0.58) | BTK | |
| SCHEMBL3199875 | 0.77 | BTK (0.66) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2242749-A1 | NOVEL PYRIDINONES AND PYRIDAZINONES | F. Hoffmann-La Roche AG (CH) | 2010-10-27 | — | — | EP | disclosed |
| WO-2009098144-A1 | NOVEL PYRIDINONES AND PYRIDAZINONES | F. HOFFMANN-LA ROCHE AG (CH) | 2009-08-13 | — | — | WO | disclosed |