SCHEMBL3671900

SCHEMBL3671900

C=Cc1cccc(CC(C)C=C)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
PTGS2 P35354 1/20 0.38
PNMT P11086 1/20 0.37
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.35
TAAR1 Q96RJ0 4/20 0.35
SLC6A2 P23975 2/20 0.34
SLC6A4 P31645 2/20 0.34
SIGMAR1 Q99720 2/20 0.34
MAOA P21397 1/20 0.34
SLC6A3 Q01959 1/20 0.34
CYP2A6 P11509 1/20 0.34
ADORA2A P29274 1/20 0.34
ADORA1 P30542 1/20 0.34
HTR2A P28223 3/20 0.34
HTR2B P41595 3/20 0.34
HTR2C P28335 2/20 0.34
FAAH O00519 1/20 0.34
HDAC8 Q9BY41 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5033169 0.85 TP53 (0.48) TP53TDP1PTGS2PNMTALDH1A1
SCHEMBL19215205 0.84 TP53 (0.47) TP53TDP1PTGS2PNMTALDH1A1
SCHEMBL5031554 0.82 TP53 (0.46) TP53TDP1PTGS2PNMTALDH1A1
SCHEMBL5034592 0.81 TP53 (0.44) TP53TDP1PTGS2PNMTALDH1A1
SCHEMBL3894782 0.79 TP53 (0.43) TP53TDP1PTGS2PNMTALDH1A1
SCHEMBL5031509 0.79 TP53 (0.46) TP53TDP1PTGS2PNMTALDH1A1
SCHEMBL5036750 0.78 TP53 (0.42) TP53TDP1PTGS2PNMTALDH1A1
SCHEMBL10881543 0.78 TP53 (0.44) TP53TDP1PTGS2PNMTALDH1A1
SCHEMBL3677179 0.77 ALDH1A1 (0.46) TP53TDP1ALDH1A1TSHRTAAR1
SCHEMBL8846364 0.77 TAAR1 (0.52) TAAR1SLC6A2SLC6A4SIGMAR1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5418276-A Styrene copolymer, syndiotactic, heat resistance, chemical resistance IDEMITSU KOSAN CO., LTD. (JP) 1995-05-23 US claimed
US-5362814-A Styrene polymers with olefin monomers and diolefin monomers for impact strength in molding materials IDEMITSU KOSAN CO., LTD. (JP) 1994-11-08 US claimed
US-8461271-B2 Graft copolymer, thermoplastic resin composition comprising the graft copolymer, and those production method IDEMITSU KOSAN CO., LTD. (JP) 2013-06-11 US disclosed
US-20100076146-A1 GRAFT COPOLYMER, THERMOPLASTIC RESIN COMPOSITION COMPRISING THE GRAFT COPOLYMER, AND THOSE PRODUCTION METHOD IDEMITSU KOSAN CO., LTD. (JP) 2010-03-25 US disclosed
US-7193013-B2 Polyolefin resin composition IDEMITSU KOSAN CO. LTD. (JP) 2007-03-20 US disclosed
EP-1367093-B1 POLYOLEFIN RESIN COMPOSITION IDEMITSU KOSAN CO (JP) 2005-12-14 EP disclosed
US-20040072950-A1 High strength, chemical resistance, weatherproofing molding materials; graft polymers IDEMITSU KOSAN CO. LTD. (JP) 2004-04-15 US disclosed
EP-0667359-B1 OLEFIN COPOLYMERS AND PROCESS FOR PRODUCING THE SAME IDEMITSU KOSAN CO (JP) 2004-03-31 EP disclosed
EP-1367093-A1 POLYOLEFIN RESIN COMPOSITION IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2003-12-03 EP disclosed
EP-0686649-B1 PROPYLENE BLOCK COPOLYMER, PROCESS FOR PRODUCING THE SAME, AND MODIFIED COPOLYMER PRODUCED THEREFROM IDEMITSU KOSAN CO (JP) 2000-08-02 EP disclosed
US-5670580-A POLYMERS FOR ANTISTATIC AGENTS, ADHESIVES AND FIREPROOFING IDEMITSU KOSAN CO., LTD. (JP) 1997-09-23 US disclosed
EP-0559108-B1 Graft copolymer, process for production thereof and resin composition containing same IDEMITSU KOSAN CO (JP) 1997-05-28 EP disclosed
US-5608009-A OLEFIN-DIOLEFIN GRAFT POLYMER IDEMITSU KOSAN CO., LTD. (JP) 1997-03-04 US disclosed
EP-0686649-A1 PROPYLENE BLOCK COPOLYMER, PROCESS FOR PRODUCING THE SAME, AND MODIFIED COPOLYMER PRODUCED THEREFROM IDEMITSU KOSAN COMPANY LIMITED (JP) 1995-12-13 EP disclosed
EP-0667359-A1 OLEFIN COPOLYMERS AND PROCESS FOR PRODUCING THE SAME IDEMITSU KOSAN COMPANY LIMITED (JP) 1995-08-16 EP disclosed
US-5418276-A Styrene copolymer, syndiotactic, heat resistance, chemical resistance IDEMITSU KOSAN CO., LTD. (JP) 1995-05-23 US disclosed
US-5362814-A Styrene polymers with olefin monomers and diolefin monomers for impact strength in molding materials IDEMITSU KOSAN CO., LTD. (JP) 1994-11-08 US disclosed
EP-0559108-A1 Graft copolymer, process for production thereof and resin composition containing same IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-09-08 EP disclosed