⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5473399 | 0.78 | — | — | |
| SCHEMBL3583741 | 0.72 | — | — | |
| SCHEMBL3425766 | 0.69 | KDM4E (0.30) | — | |
| SCHEMBL9754058 | 0.69 | — | — | |
| SCHEMBL222319 | 0.67 | — | — | |
| SCHEMBL1766323 | 0.67 | — | — | |
| SCHEMBL27555 | 0.67 | — | — | |
| SCHEMBL207518 | 0.67 | — | — | |
| SCHEMBL1766935 | 0.67 | — | — | |
| SCHEMBL209664 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9487494-B2 | Cyclic hydrocarbon compounds for the treatment of diseases | LEO PHARMA A/S (DK) | 2016-11-08 | — | — | US | claimed |
| US-20100317582-A1 | NOVEL CYCLIC HYDROCARBON COMPOUNDS FOR THE TREATMENT OF DISEASES | LEO PHARMA A/S (DK) | 2010-12-16 | — | — | US | claimed |
| EP-2234961-A2 | NOVEL CYCLIC HYDROCARBON COMPOUNDS FOR THE TREATMENT OF DISEASES | LEO PHARMA A/S (DK) | 2010-10-06 | — | — | EP | claimed |
| WO-2009065406-A2 | NOVEL CYCLIC HYDROCARBON COMPOUNDS FOR THE TREATMENT OF DISEASES | LEO PHARMA A/S (DK) | 2009-05-28 | — | — | WO | claimed |
| CN-1617729-A | Use of benzothiazepines having activity as inhibitors of ileal bile acid transport for reducing cholesterololemia | ASTRAZENECA AB (SE) | 2005-05-18 | — | — | CN | claimed |
| CN-108341943-A | A kind of hydridization dynamic aggregation object and its application | 翁秋梅 | 2018-07-31 | — | — | CN | disclosed |
| CN-108341951-A | A kind of dynamic aggregation object and its application with hybrid cross-linked structure | 翁秋梅 | 2018-07-31 | — | — | CN | disclosed |
| CN-107805311-A | A kind of dynamic aggregation thing and its application with hybrid cross-linked network | 翁秋梅 | 2018-03-16 | — | — | CN | disclosed |
| CN-107805308-A | A kind of dynamic aggregation thing and its application with hybrid cross-linked network | 翁秋梅 | 2018-03-16 | — | — | CN | disclosed |
| US-9487494-B2 | Cyclic hydrocarbon compounds for the treatment of diseases | LEO PHARMA A/S (DK) | 2016-11-08 | — | — | US | disclosed |
| US-20100317582-A1 | NOVEL CYCLIC HYDROCARBON COMPOUNDS FOR THE TREATMENT OF DISEASES | LEO PHARMA A/S (DK) | 2010-12-16 | — | — | US | disclosed |
| EP-2234961-A2 | NOVEL CYCLIC HYDROCARBON COMPOUNDS FOR THE TREATMENT OF DISEASES | LEO PHARMA A/S (DK) | 2010-10-06 | — | — | EP | disclosed |
| EP-1979354-B1 | DIAZA-SPIRO-[4, 5]-DECANES USEFUL AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-11-11 | — | — | EP | disclosed |
| WO-2009065406-A2 | NOVEL CYCLIC HYDROCARBON COMPOUNDS FOR THE TREATMENT OF DISEASES | LEO PHARMA A/S (DK) | 2009-05-28 | — | — | WO | disclosed |
| US-20080026486-A1 | Assay Methods, Materials and Preparations | AKUBIO LIMITED (GB) | 2008-01-31 | — | — | US | disclosed |
| EP-1799720-A1 | ASSAY METHODS, MATERIALS AND PREPARATIONS | Akubio Limited (GB) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006027582-A1 | ASSAY METHODS, MATERIALS AND PREPARATIONS | AKUBIO LIMITED (GB) | 2006-03-16 | — | — | WO | disclosed |
| CN-1617729-A | Use of benzothiazepines having activity as inhibitors of ileal bile acid transport for reducing cholesterololemia | ASTRAZENECA AB (SE) | 2005-05-18 | — | — | CN | disclosed |