SCHEMBL3672006

SCHEMBL3672006

CC(C)(Oc1ccc(Oc2ncc(C(F)(F)F)cc2Cl)cc1)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 6/20 0.66
LMNA P02545 7/20 0.62
LIPE Q05469 1/20 0.61
FFAR1 O14842 1/20 0.59
RAB9A P51151 1/20 0.58
ALDH1A1 P00352 5/20 0.56
HTT P42858 4/20 0.54
MAPT P10636 3/20 0.54
KMT2A Q03164 2/20 0.54
XBP1 P17861 2/20 0.54
MEN1 O00255 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
ATM Q13315 1/20 0.53
HPGD P15428 3/20 0.53
POLB P06746 1/20 0.53
KDM4E B2RXH2 1/20 0.51
TDP1 Q9NUW8 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6916180 0.88 LMNA (0.66) SMN1; SMN2LMNALIPEFFAR1RAB9A
SCHEMBL28371036 0.85 PPARA (0.55) SMN1; SMN2LMNALIPEFFAR1MAPT
SCHEMBL11005278 0.85 SMN1; SMN2 (0.62) SMN1; SMN2LMNALIPEFFAR1RAB9A
SCHEMBL11360493 0.83 SMN1; SMN2 (0.71) SMN1; SMN2LMNALIPEFFAR1RAB9A
SCHEMBL28343740 0.83 SMN1; SMN2 (0.57) SMN1; SMN2LMNALIPEFFAR1RAB9A
SCHEMBL9362409 0.83 SMN1; SMN2 (0.57) SMN1; SMN2LMNALIPEFFAR1RAB9A
SCHEMBL6840320 0.83 SMN1; SMN2 (0.72) SMN1; SMN2LMNALIPEFFAR1RAB9A
SCHEMBL20626582 0.83 SMN1; SMN2 (0.72) SMN1; SMN2LMNALIPEFFAR1RAB9A
SCHEMBL8795409 0.81 SMN1; SMN2 (0.58) SMN1; SMN2LMNALIPEFFAR1RAB9A
SCHEMBL10715450 0.81 SMN1; SMN2 (0.58) SMN1; SMN2LMNALIPEFFAR1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0613618-B1 Method for safening herbicides in crops using substituted benzopyran and tetrahydronaphthalene compounds AMERICAN CYANAMID CO (US) 1997-04-16 EP claimed
EP-0496608-B1 Substituted pyridinesulfonamide compound or its salt, process for preparing the same, and herbicide containing the same ISHIHARA SANGYO KAISHA (JP) 1995-09-20 EP claimed
EP-0212200-B1 PYRIDINE DERIVATIVES AND HERBICIDAL COMPOSITION NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1993-03-24 EP claimed
EP-0212200-A2 Pyridine derivatives and herbicidal composition NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1987-03-04 EP claimed
WO-2025008790-A1 STABLE SYNERGISTIC HERBICIDAL COMPOSITION MUNJAL SMITA (IN) 2025-01-09 WO disclosed
US-9232796-B2 Herbicidal compositions comprising 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl) pyridine-2-carboxylic acid or a derivative thereof and acetyl-CoA carboxylase (ACCase) inhibitors DOW AGROSCIENCES LLC (US) 2016-01-12 US disclosed
US-20150189879-A1 HERBICIDAL COMPOSITIONS COMPRISING 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL) PYRIDINE-2-CARBOXYLIC ACID OR A DERIVATIVE THEREOF AND ACETYL-CoA CARBOXYLASE (ACCASE) INHIBITORS CORTEVA AGRISCIENCE LLC 2015-07-09 US disclosed
US-20100075854-A1 HERBICIDE COMBINATION COMPRISING DIMETHOSXYTRIAZINYL-SUBSTITUTED DIFLUOROMETHANESULFONYLANILIDES BAYER CROPSCIENCE AG (DE) 2010-03-25 US disclosed
EP-1784075-A2 HERBICIDE COMBINATIONS COMPRISING SPECIAL KETOENOLES Bayer CropScience GmbH (DE) 2007-05-16 EP disclosed
WO-2006024411-A2 HERBICIDE COMBINATIONS COMPRISING SPECIAL KETOENOLES BAYER CROPSCIENCE GMBH (DE) 2006-03-09 WO disclosed
EP-1410715-A1 Combinations of aryloxyphenoxypropionates and safeners and their use for increasing weed control Bayer CropScience GmbH (DE) 2004-04-21 EP disclosed
EP-0356812-B1 ADJUVANTS FOR USE WITH CROP PROTECTION AGENTS BASF Corporation (US) 1993-08-04 EP disclosed
US-5039331-A Condensed heterocyclic derivatives and herbicides NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1991-08-13 US disclosed
US-4988818-A Herbicides BASF AKTIENGESELLSCHAFT (DE) 1991-01-29 US disclosed
US-4963690-A HERBICIDE SYNERGISTS BASF AKTIENGESELLSCHAFT (DE) 1990-10-16 US disclosed
EP-0356812-A2 Adjuvants for use with crop protection agents BASF Corporation (US) 1990-03-07 EP disclosed
US-4824474-A Quinoline derivatives and herbicidal compositions and method of use thereof NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1989-04-25 US disclosed
EP-0304920-A2 Condensed heterocyclic derivatives, process for their production and herbicides NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1989-03-01 EP disclosed
US-4696694-A Pyridine derivatives and their herbicidal compositions NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1987-09-29 US disclosed
EP-0212200-A2 Pyridine derivatives and herbicidal composition NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1987-03-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150189879-A1 HERBICIDAL COMPOSITIONS COMPRISING 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL) PYRIDINE-2-CARBOXYLIC ACID OR A DERIVATIVE THEREOF AND ACETYL-CoA CARBOXYLASE (ACCASE) INHIBITORS FAH, DDT, NOTUM SMN1; SMN2 4831/4885LMNA 4352/4885LIPE 314/4885
US-20100075854-A1 HERBICIDE COMBINATION COMPRISING DIMETHOSXYTRIAZINYL-SUBSTITUTED DIFLUOROMETHANESULFONYLANILIDES DDT, CYP4F12, CYP4F2 SMN1; SMN2 4642/4885LMNA 4565/4885LIPE 3865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.