Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.93 |
| ▸ | DAO | P14920 | 1/20 | 0.93 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.93 |
| ▸ | CES2 | O00748 | 3/20 | 0.74 |
| ▸ | CES1 | P23141 | 3/20 | 0.74 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.74 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA3 | P07451 | 2/20 | 0.55 |
| ▸ | CA4 | P22748 | 2/20 | 0.55 |
| ▸ | CA6 | P23280 | 2/20 | 0.55 |
| ▸ | CA5A | P35218 | 2/20 | 0.55 |
| ▸ | CA7 | P43166 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL21634193 | 1.00 | TSHR (0.93) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL5490800 | 1.00 | TSHR (0.93) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL21634192 | 1.00 | TSHR (0.93) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL9396733 | 1.00 | TSHR (0.93) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL1813391 | 1.00 | TSHR (0.93) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL1065043 | 1.00 | TSHR (0.93) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL8640540 | 0.97 | TSHR (0.88) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL31520026 | 0.97 | TSHR (0.88) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL28520812 | 0.97 | TSHR (0.88) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL395154 | 0.97 | TSHR (0.88) | TSHRDAONAPRTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 7442 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4739278-A1 | ANIMAL TREAT FOR ANIMAL ORAL HYGIENE | Dentalis Animal Health Inc. (CA) | 2026-05-13 | — | — | EP | claimed |
| CN-122006498-A | Preparation method of PTFE porous non-woven fiber membrane and PTFE porous non-woven fiber membrane | 高能数造(西安)技术有限公司 | 2026-05-12 | — | — | CN | claimed |
| US-20260125565-A1 | A WATERBORNE COATING COMPOSITION COMPRISING A DISPERSED NON-SENSITIZING ANTI-MICROBIAL COMPOSITION | PERSTORP AB (SE) | 2026-05-07 | — | — | US | claimed |
| EP-4493286-B1 | A SOLID CLEANSING COMPOSITION | UNILEVER IP HOLDINGS B V (NL) | 2026-05-06 | — | — | EP | claimed |
| CN-121583778-A | Electrolyte of aluminum electrolytic capacitor, preparation method and aluminum electrolytic capacitor | 益阳市安兴电子有限公司 | 2026-02-27 | — | — | CN | claimed |
| US-12553872-B2 | Colorimetric quantification of corrosion inhibitor compounds in industrial fluids | NORTHERN TECH INTERNATIONAL CORPORATION (US) | 2026-02-17 | — | — | US | claimed |
| US-12516421-B2 | Barrier chemical mechanical planarization slurries for cobalt films | VERSUM MATERIALS US, LLC (US) | 2026-01-06 | — | — | US | claimed |
| US-12451489-B2 | Anode material, preparation method thereof and battery | BTR NEW MATERIAL GROUP CO., LTD. (CN) | 2025-10-21 | — | — | US | claimed |
| US-12403074-B2 | Process for permanent waving keratin fibers | KAO GERMANY GMBH (DE) | 2025-09-02 | — | — | US | claimed |
| US-20250268823-A1 | Aqueous Quetiapine Solutions | RELIIS LTD. (AU) | 2025-08-28 | — | — | US | claimed |
| US-4095030-A | CARBOXYLIC ACID SALTS, DILUENTS | PHILLIPS PETROLEUM COMPANY (US) | 1978-06-13 | — | — | US | claimed |
| US-4092314-A | FROM ARYLAZOMALONONITRILE AND FORMAMIDE AND AMMONIA, AMMONIUM SALT | MERCK & CO., INC. (US) | 1978-05-30 | — | — | US | claimed |
| US-4040838-A | NON-POLLUTING BLEACH OR BLIX SOLUTION; METAL COMPLEX OF ORGANIC ACID, AMMONIUM COMPOUND, MAGNESIUM COMPOUND | FUJI PHOTO FILM CO., LTD. (JA) | 1977-08-09 | — | — | US | claimed |
| US-4020182-A | HYDRAZINIUM AND AMMONIUM SALTS, SAFE | Burt, Leo E. (US) | 1977-04-26 | — | — | US | claimed |
| US-3989640-A | SYNERGISTIC, MORPHOLINE, AMMONIUM BENZOATE AND CYCLOHEXANE OR NITROPROPANE OR CYCLOPENTENE | THE DRACKETT COMPANY (US) | 1976-11-02 | — | — | US | claimed |
| US-RE28957-E | Synthetic resin compositions and methods of utilizing the same | JOHNSON & JOHNSON (US) | 1976-09-07 | — | — | US | claimed |
| US-3956299-A | HEATING UREA OR BIURET, BY-PRODUCT INHIBITION | STAMICARBON B.V. (NL) | 1976-05-11 | — | — | US | claimed |
| US-3953344-A | THERMOPLASTIC RESIN, GROUP 2A METAL SOAP, CORROSION INHIBITOR | NIPPON PAINT CO., LTD. (JA) | 1976-04-27 | — | — | US | claimed |
| US-3931208-A | Process for the production of thiazolines-(3) | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1976-01-06 | — | — | US | claimed |
| US-3931085-A | POLYVALENT METAL COMPLEX | JOHNSON & JOHNSON (US) | 1976-01-06 | — | — | US | claimed |