Pyridine

Pyridine

SCHEMBL367212

CCCCCl.c1ccncc1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.55
TDP1 Q9NUW8 3/20 0.55
NAPRT Q6XQN6 1/20 0.45
ALDH1A1 P00352 3/20 0.43
CYP2D6 P10635 3/20 0.36
CYP3A4 P08684 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CYP2C9 P11712 3/20 0.35
CYP2C19 P33261 3/20 0.35
MAPT P10636 3/20 0.35
CYP19A1 P11511 2/20 0.35
POLB P06746 1/20 0.35
CYP1A2 P05177 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
MEN1 O00255 1/20 0.32
MAPK1 P28482 1/20 0.32
CASP2 P42575 1/20 0.32
KMT2A Q03164 1/20 0.32
HSPD1 P10809 1/20 0.31
RAD52 P43351 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL988718 0.93 TSHR (0.55) TSHRTDP1NAPRTALDH1A1CYP2D6
Pyridine SCHEMBL2762938 0.91 TSHR (0.59) TSHRTDP1NAPRTALDH1A1L3MBTL1
Pyridine SCHEMBL3912001 0.91 TSHR (0.59) TSHRTDP1NAPRTALDH1A1L3MBTL1
Pyridine SCHEMBL43361 0.91 TSHR (0.59) TSHRTDP1NAPRTALDH1A1L3MBTL1
Pyridine SCHEMBL160900 0.91 TSHR (0.59) TSHRTDP1NAPRTALDH1A1L3MBTL1
Pyridine SCHEMBL313836 0.91 TSHR (0.59) TSHRTDP1NAPRTALDH1A1L3MBTL1
Pyridine SCHEMBL1258383 0.91 TSHR (0.59) TSHRTDP1NAPRTALDH1A1L3MBTL1
Pyridine SCHEMBL7142445 0.91 TSHR (0.59) TSHRTDP1NAPRTALDH1A1L3MBTL1
Pyridine SCHEMBL21641467 0.91 TSHR (0.59) TSHRTDP1NAPRTALDH1A1L3MBTL1
Pyridine SCHEMBL1389613 0.91 TSHR (0.59) TSHRTDP1NAPRTALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 479 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106964345-B A kind of noble metal porous nano film and preparation method thereof 武汉理工大学 2019-08-27 CN claimed
CN-106964345-A A kind of noble metal porous nano film and preparation method thereof 武汉理工大学 2017-07-21 CN claimed
CN-104911650-A Novel electroplating solution for gallium plating LIANG SHENGGUANG 2015-09-16 CN claimed
US-8715853-B1 Aluminum batteries comprising metal-oxide, metal-fluoride, metal-sulfide, or sulfur cathodes HRL LABORATORIES, LLC (US) 2014-05-06 US claimed
US-20120136189-A1 BUFFERED IONIC LIQUIDS FOR OLEFIN DIMERIZATION CONOCOPHILLIPS COMPANY - IP SERVICES GROUP (US) 2012-05-31 US claimed
WO-2011112514-A1 BUFFERED IONIC LIQUIDS FOR OLEFIN DIMERIZATION CONOCOPHILLIPS COMPANY (US) 2011-09-15 WO claimed
US-20110185788-A1 IONIC LIQUIDS AS SOLVENTS IN HEADSPACE GAS CHROMATOGRAPHY KOCH PETER 2011-08-04 US claimed
EP-2275090-A2 Microparticles prepared using an ionic liquid Novartis AG (CH) 2011-01-19 EP claimed
US-20100239524-A1 MICROPARTICLES PREPARED USING AN IONIC LIQUID NOVARTIS AG (CH) 2010-09-23 US claimed
US-7569149-B2 Ionic liquids as solvents in headspace gas chromatography NOVARTIS AG (CH) 2009-08-04 US claimed
US-5994602-A IN THE PRESENCE OF A HYDROCARBYL ALUMINUM OR GALLIUM HALIDE AND A HYDROCARBYL-SUBSTITUTED IMIDAZOLIUM OR PYRIDINIUM HALIDE BP CHEMICALS LIMITED (GB) 1999-11-30 US claimed
WO-1998047616-A1 CATALYST COMPRISING A BUFFERED IONIC LIQUID AND HYDROCARBON CONVERSION PROCESS, E.G. OLIGOMERISATION BP CHEMICALS LIMITED (GB) 1998-10-29 WO claimed
EP-0693045-B1 ALKYLATION PROCESS BP CHEM INT LTD (GB) 1997-10-22 EP claimed
EP-0791643-A1 Lubricating oils BP Chemicals Limited (GB) 1997-08-27 EP claimed
US-5643490-A HETEROCYCLIC CATIONIC POLYMER FOR ELECTROLYTES SONY CORPORATION (JP) 1997-07-01 US claimed
US-5550306-A Catalytic process for the dimerization of olefins INSTITUT FRANCAIS DU PETROLE (FR) 1996-08-27 US claimed
EP-0693045-A1 ALKYLATION PROCESS BP CHEM INT LTD (GB) 1996-01-24 EP claimed
WO-1995021872-A1 IONIC LIQUIDS BP CHEMICALS LIMITED (GB) 1995-08-17 WO claimed
WO-1995021806-A1 ALKYLATION PROCESS BP CHEMICALS LIMITED (GB) 1995-08-17 WO claimed
US-4355086-A IMPROVED WITH ALUMINUM CHLORIDE AND BUTYL PYRIDINIUM CHLORIDE HONEYWELL INC. (US) 1982-10-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100239524-A1 MICROPARTICLES PREPARED USING AN IONIC LIQUID FIBP, MIF, CHMP4B TSHR 3760/4885TDP1 1587/4885NAPRT 4128/4885
US-20120136189-A1 BUFFERED IONIC LIQUIDS FOR OLEFIN DIMERIZATION OSBPL8, OSBP, OSBP2 TSHR 2589/4885TDP1 2022/4885NAPRT 2710/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.