SCHEMBL3672157

SCHEMBL3672157

NC(N)Cc1ccc(Br)cc1

nearest known ligand 0.67

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 5/20 0.48
HTR2A P28223 1/20 0.48
IDO1 P14902 4/20 0.46
CYP2A6 P11509 1/20 0.42
SLC6A4 P31645 1/20 0.41
ALDH1A1 P00352 1/20 0.39
ALOX15 P16050 1/20 0.39
MAPK1 P28482 1/20 0.39
MAOA P21397 1/20 0.39
EPHX1 P07099 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2617234 0.80 TAAR1 (0.61) TAAR1CYP2A6SLC6A4MAOA
SCHEMBL3041534 0.80 TAAR1 (0.44) TAAR1HTR2AIDO1CYP2A6SLC6A4
SCHEMBL164716 0.80 TAAR1 (0.61) TAAR1CYP2A6SLC6A4MAOA
SCHEMBL2617233 0.80 TAAR1 (0.61) TAAR1CYP2A6SLC6A4MAOA
Hydrochloric Acid SCHEMBL30559541 0.78 TAAR1 (0.59) TAAR1CYP2A6SLC6A4MAOA
SCHEMBL1177250 0.78 SLC6A4 (0.46) TAAR1HTR2AIDO1SLC6A4EPHX1
SCHEMBL5234787 0.78 SLC6A4 (0.46) TAAR1HTR2AIDO1SLC6A4EPHX1
Hydrochloric Acid SCHEMBL17674512 0.78 TAAR1 (0.59) TAAR1CYP2A6SLC6A4MAOA
SCHEMBL24380871 0.77 TAAR1 (0.41) TAAR1HTR2AIDO1EPHX1
Bromide SCHEMBL8209117 0.77 CYP1A2 (0.55) TAAR1HTR2AIDO1CYP2A6SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1426392-B1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL CO (JP) 2010-02-24 EP disclosed
US-6960640-B2 Composition for optical material MITSUBISHI GAS CHEMICAL CO., LTD. (JP) 2005-11-01 US disclosed
US-20040147708-A1 Composition for optical material MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-07-29 US disclosed
EP-1426392-A1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-06-09 EP disclosed