SCHEMBL164716

SCHEMBL164716

CC(N)Cc1ccc(Br)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 5/20 0.61
SLC6A2 P23975 5/20 0.61
SLC6A3 Q01959 3/20 0.61
SLC6A4 P31645 3/20 0.60
MAOA P21397 2/20 0.60
SIGMAR1 Q99720 1/20 0.60
CYP2A6 P11509 1/20 0.60
ADORA2A P29274 1/20 0.60
ADORA1 P30542 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2617233 1.00 TAAR1 (0.61) TAAR1SLC6A2SLC6A3SLC6A4MAOA
SCHEMBL2617234 1.00 TAAR1 (0.61) TAAR1SLC6A2SLC6A3SLC6A4MAOA
Hydrochloric Acid SCHEMBL17674512 0.98 TAAR1 (0.59) TAAR1SLC6A2SLC6A3SLC6A4MAOA
Hydrochloric Acid SCHEMBL30559541 0.98 TAAR1 (0.59) TAAR1SLC6A2SLC6A3SLC6A4MAOA
SCHEMBL10872752 0.87 TAAR1 (0.76) TAAR1SLC6A2SLC6A3SLC6A4MAOA
SCHEMBL10872755 0.87 TAAR1 (0.76) TAAR1SLC6A2SLC6A3SLC6A4MAOA
SCHEMBL10525345 0.86 TAAR1 (0.47) TAAR1SLC6A2SLC6A3SLC6A4MAOA
Hydrochloric Acid SCHEMBL4683910 0.80 CYP2D6 (0.61) TAAR1SLC6A2SLC6A3SLC6A4MAOA
SCHEMBL3672157 0.80 TAAR1 (0.48) TAAR1SLC6A4MAOACYP2A6
SCHEMBL10775150 0.80 TAAR1 (0.67) TAAR1SLC6A2SLC6A3SLC6A4MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 249 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250340587-A1 INSOLUBLE SUPPORT FOR SOLID PHASE SYNTHESIS POLYPEPTIDE LABORATORIES HOLDING PPL AB (SE) 2025-11-06 US claimed
CN-119678852-A Breeding method for excellent seedlings of dendrobium nobile in tropical rain forest 海南乾景越实业集团有限公司 2025-03-25 CN claimed
EP-4444283-A1 SPECIALIZED COMBINATIONS FOR MENTAL DISORDERS OR MENTAL ENHANCEMENT Tactogen Inc. (US) 2024-10-16 EP claimed
CN-118526582-A Bioorthogonal chemical method for activating active molecules by infrared remote control 北京大学 2024-08-23 CN claimed
CN-117486960-A Preparation method of cholesterol and intermediate thereof 苏州保尔朴生物医药科技有限公司 2024-02-02 CN claimed
WO-2023107715-A1 SPECIALIZED COMBINATIONS FOR MENTAL DISORDERS OR MENTAL ENHANCEMENT TACTOGEN INC (US) 2023-06-15 WO claimed
CN-114315947-A Novel method for synthesizing cholesterol and 25-hydroxycholesterol by using 22-sterol as raw material 上海敏韬医药科技有限公司 2022-04-12 CN claimed
CN-111777540-A Method for synthesizing pyrrolidone compound by continuous light-induced catalysis 南京工业大学 2020-10-16 CN claimed
WO-2019200940-A1 PEROVSKITE THIN FILM AND PREPARATION METHOD THEREFOR, PEROVSKITE ELECTROLUMINESCENT DEVICE AND PREPARATION METHOD THEREFOR, AND DISPLAY DEVICE 京东方科技集团股份有限公司 2019-10-24 WO claimed
CN-122032659-A Modified macroporous strong alkali anion resin and preparation method and application thereof 中国科学院青海盐湖研究所 2026-05-15 CN disclosed
US-12599578-B2 Compositions comprising enzyme-cleavable prodrugs and controlled release nafamostat and methods of use thereof Ensysce Biosciences Inc. (US) 2026-04-14 US disclosed
EP-4720038-A1 (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES Neophore Limited (GB) 2026-04-08 EP disclosed
US-20260048567-A1 METHOD, DECORATIVE FILM AND HIGH-PERFORMANCE COATING FOR DECORATING AND EMBOSSING A MATERIAL MACOR GIORGIO (IT) 2026-02-19 US disclosed
EP-4683622-A1 NON-DISTILLATIVE PROCESS FOR MANUFACTURING HIGH PURITY AMPHETAMINES Pharmapotheca A, Inc. (US) 2026-01-28 EP disclosed
EP-0507863-A4 SIGMA RECEPTOR LIGANDS AND THE USE THEREOF 1993-07-07 EP disclosed
WO-1993000313-A2 SIGMA RECEPTOR LIGANDS AND THE USE THEREOF VIRGINIA COMMONWEALTH UNIVERSITY (US) 1993-01-07 WO disclosed
EP-0507863-A1 SIGMA RECEPTOR LIGANDS AND THE USE THEREOF VIRGINIA COMMONWEALTH UNIVERSITY (US) 1992-10-14 EP disclosed
WO-1991009594-A1 SIGMA RECEPTOR LIGANDS AND THE USE THEREOF VIRGINIA COMMONWEALTH UNIVERSITY (US) 1991-07-11 WO disclosed
US-4857553-A SIDE EFFECT REDUCTION A. H. ROBINS COMPANY, INCORPORATED (US) 1989-08-15 US disclosed
EP-0302757-A2 Anti-emetic serotonin depleting agents A.H. ROBINS COMPANY, INCORPORATED (US) 1989-02-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250340587-A1 INSOLUBLE SUPPORT FOR SOLID PHASE SYNTHESIS SSU72, CPSF6, IDUA TAAR1 2604/4885SLC6A2 4020/4885SLC6A3 3673/4885
US-20260048567-A1 METHOD, DECORATIVE FILM AND HIGH-PERFORMANCE COATING FOR DECORATING AND EMBOSSING A MATERIAL EMD, LIN28A, TMPO TAAR1 1354/4885SLC6A2 1452/4885SLC6A3 2184/4885
US-12599578-B2 Compositions comprising enzyme-cleavable prodrugs and controlled release nafamostat and methods of use thereof OPRK1, OPRL1, OPRM1 TAAR1 543/4885SLC6A2 1385/4885SLC6A3 779/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.