SCHEMBL3672158

SCHEMBL3672158

CCOC(=O)c1cnn(C)c1S(=O)(=O)N(C(N)=O)c1nc(OC)cc(OC)n1

nearest known ligand 0.59

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.38
TSHR P16473 2/20 0.38
MEN1 O00255 1/20 0.38
POLB P06746 1/20 0.36
RAB9A P51151 3/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
NPC1 O15118 2/20 0.36
MAPT P10636 2/20 0.36
KDM4E B2RXH2 2/20 0.35
ALDH1A1 P00352 6/20 0.34
HPGD P15428 1/20 0.34
CSNK1D P48730 1/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9565706 0.92 KMT2A (0.37) KMT2ATSHRMEN1POLBRAB9A
SCHEMBL1535828 0.90 KMT2A (0.45) KMT2ATSHRSMN1; SMN2KDM4EALDH1A1
SCHEMBL9565721 0.88 TSHR (0.41) KMT2ATSHRMEN1RAB9ASMN1; SMN2
SCHEMBL9061697 0.87 MAPT (0.38) KMT2ATSHRMEN1RAB9ASMN1; SMN2
SCHEMBL8465071 0.86 KMT2A (0.36) KMT2ATSHRMEN1POLBSMN1; SMN2
SCHEMBL9729213 0.84 TSHR (0.40) KMT2ATSHRMEN1RAB9ASMN1; SMN2
SCHEMBL9566133 0.81 KMT2A (0.48) KMT2ATSHRMEN1RAB9ASMN1; SMN2
Chlorsulfuron SCHEMBL10441299 0.80 KDM4E (0.44) SMN1; SMN2NPC1KDM4EALDH1A1
SCHEMBL18209763 0.75 CYP1A2 (0.42) KMT2ATSHRMEN1RAB9ASMN1; SMN2
Pyrazosulfuron Ethyl SCHEMBL369569 0.75 GAA (0.45) KMT2ATSHRMEN1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050170964-A1 Herbicidal composition and method of weeding with the same KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2005-08-04 US claimed
EP-0861026-B1 SYNERGISTIC HERBICIDAL MIXTURES CONTAINING CYCLOHEXENONE OXIME ETHER BASF AG (DE) 2003-04-02 EP claimed
US-20020165094-A1 Herbicidal synergistic composition, and method of controlling weeds ALLARD JEAN LOUIS (CH) 2002-11-07 US claimed
US-6103664-A Synergistic herbicidal mixtures containing cyclohexenone oxime ethers BASF AKTIENGESELLSCHAFT (DE) 2000-08-15 US claimed
US-6066596-A CONTAINING ETHYL 5-(4,6-DIMETHOXYPYRIMIDIN-2-YL-CARBAMOYLSULFAMOYL)-1-METHYLPYR AZOLE-4-CARBOXYLATE NOVARTIS CORPORATION (US) 2000-05-23 US claimed
EP-0714602-B1 Sulphonylaminophenyluracil herbicides for paddy field BAYER AGROCHEM KK (JP) 1999-05-12 EP claimed
EP-0708597-B1 HERBICIDAL COMPOSITIONS RHONE POULENC AGROCHIMIE (FR) 1998-09-16 EP claimed
EP-0768034-B1 Synergistic herbicidal composition and method for weed control CIBA GEIGY AG (CH) 1998-08-12 EP claimed
US-5672566-A MIXTURES OF 6-ALKYL-3-ALKYL(OR HALOALKYL-)PHENYL-5-PHENYL 2,3-DIHYDRO-4H-1,3-OXAZIN-4-ONES WITH OTHER HERBICIDES RHONE-POULENC AGROCHIMIE (FR) 1997-09-30 US claimed
US-5641725-A Sulphonylaminophenyluracil herbicides for paddy field NIHON BAYER AGROCHEM K.K. (JP) 1997-06-24 US claimed
EP-0714602-A1 Sulphonylaminophenyluracil herbicides for paddy field NIHON BAYER AGROCHEM K.K. (JP) 1996-06-05 EP claimed
EP-0708597-A1 HERBICIDAL COMPOSITIONS RHONE-POULENC AGROCHIMIE (FR) 1996-05-01 EP claimed
WO-1995002329-A1 HERBICIDAL COMPOSITIONS RHONE-POULENC AGROCHIMIE (FR) 1995-01-26 WO claimed
EP-0471284-B1 Herbicidal compositions IDEMITSU KOSAN CO (JP) 1995-01-18 EP claimed
US-5234893-A Post and pre-emergence; borad leaf weeds and gramineae weeds IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-08-10 US claimed
EP-0471284-A1 Herbicidal compositions IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-02-19 EP claimed
JP-8034702-A None JP disclosed
JP-1093503-A None JP disclosed
JP-H0193503-A HERBICIDAL COMPOSITION KUMIAI CHEM IND CO LTD 1989-04-12 JP disclosed
JP-H00193503-A 0001-01-01 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020165094-A1 Herbicidal synergistic composition, and method of controlling weeds DDT, CBR3, HACL2 KMT2A 1807/4885TSHR 1896/4885MEN1 3962/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.