Pyrazosulfuron Ethyl

Pyrazosulfuron Ethyl

SCHEMBL369569

CC(N)=O.CCOC(=O)c1cnn(C)c1S(=O)(=O)NC(=O)Nc1nc(OC)cc(OC)n1

nearest known ligand 0.93

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.45
CDK1 P06493 1/20 0.40
CYP1A2 P05177 1/20 0.39
MAPT P10636 2/20 0.38
ALDH1A1 P00352 2/20 0.38
KDM4E B2RXH2 1/20 0.38
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.36
TSHR P16473 1/20 0.36
TP53 P04637 1/20 0.35
GLA P06280 1/20 0.35
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrazosulfuron Ethyl SCHEMBL22006 0.96 GAA (0.48) GAACDK1CYP1A2MAPTALDH1A1
Pyrazosulfuron Ethyl SCHEMBL15513045 0.95 GAA (0.47) GAACDK1CYP1A2MAPTALDH1A1
Pyrazosulfuron Ethyl SCHEMBL15524983 0.95 GAA (0.47) GAACDK1CYP1A2MAPTALDH1A1
Pyrazosulfuron Ethyl SCHEMBL2440654 0.93 GAA (0.45) GAACDK1CYP1A2MAPTALDH1A1
SCHEMBL9195352 0.92 GAA (0.44) GAACDK1MAPTALDH1A1KDM4E
Pyrazosulfuron Ethyl SCHEMBL15540353 0.89 GAA (0.41) GAACDK1CYP1A2MAPTALDH1A1
SCHEMBL3404171 0.89 GAA (0.39) GAAMAPTALDH1A1KDM4EKMT2A
SCHEMBL1535829 0.87 GAA (0.53) GAACDK1CYP1A2MAPTALDH1A1
SCHEMBL10575713 0.87 MAPT (0.39) GAACYP1A2MAPTALDH1A1KDM4E
SCHEMBL9661255 0.85 GAA (0.53) GAACDK1CYP1A2MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1531670-B1 HERBICIDAL COMPOSITION SYNGENTA PARTICIPATIONS AG (CH) 2015-12-09 EP disclosed
US-8551918-B2 Herbicidal composition SYNGENTA CROP PROTECTION LLC (US) 2013-10-08 US disclosed
US-8097561-B2 Herbicidal composition SYNGENTA CROP PROTECTION, INC. (US) 2012-01-17 US disclosed
US-20070197387-A1 Herbicidal Composition SYNGENTA PARTICIPATIONS AG (CH) 2007-08-23 US disclosed
EP-1689227-A2 HERBICIDAL COMPOSITION Syngenta Participations AG (CH) 2006-08-16 EP disclosed
EP-1531670-A4 HERBICIDAL COMPOSITION SYNGENTA PARTICIPATIONS AG (CH) 2005-11-23 EP disclosed
US-20050233907-A1 Herbicidal composition SYNGENTA CROP PROTECTION AG (CH) 2005-10-20 US disclosed
WO-2005055716-A2 HERBICIDAL COMPOSITION SYNGENTA PARTICIPATIONS AG (CH) 2005-06-23 WO disclosed
EP-1531670-A1 HERBICIDAL COMPOSITION Syngenta Participations AG (CH) 2005-05-25 EP disclosed
WO-2003105587-A1 HERBICIDAL COMPOSITION SYNGENTA PARTICIPATIONS AG (CH) 2003-12-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050233907-A1 Herbicidal composition ADH5, ADH1C, AQP3 GAA 1060/4885CDK1 4310/4885CYP1A2 83/4885
US-20070197387-A1 Herbicidal Composition DDT, HDHD5, DERL1 GAA 652/4885CDK1 2483/4885CYP1A2 40/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.