Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.70 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.70 |
| ▸ | KDR | P35968 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.61 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.61 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.61 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.61 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12443228 | 0.89 | MAPT (0.74) | NTRK1CDK19KDRMAPTKMT2A | |
| SCHEMBL3692790 | 0.87 | KDR (0.73) | NTRK1CDK19KDRMAPTKMT2A | |
| SCHEMBL4349868 | 0.87 | EPHX2 (0.67) | NTRK1CDK19KDRMAPTKMT2A | |
| SCHEMBL665533 | 0.86 | KDR (0.67) | NTRK1CDK19KDRMAPTKMT2A | |
| SCHEMBL30413950 | 0.86 | KDR (0.67) | NTRK1CDK19KDRMAPTKMT2A | |
| SCHEMBL30101230 | 0.85 | KMT2A (0.90) | NTRK1CDK19KDRMAPTKMT2A | |
| SCHEMBL5597699 | 0.85 | KMT2A (0.90) | NTRK1CDK19KDRMAPTKMT2A | |
| SCHEMBL14601707 | 0.84 | KMT2A (0.77) | NTRK1CDK19KDRMAPTKMT2A | |
| SCHEMBL13549872 | 0.84 | MAPT (0.70) | NTRK1CDK19MAPTKMT2AMEN1 | |
| SCHEMBL4548162 | 0.83 | KMT2A (0.87) | NTRK1CDK19KDRMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100234349-A1 | PHARMACEUTICAL COMBINATIONS OF A NICOTINE RECEPTOR MODULATOR AND A COGNITIVE ENHANCER | NEUROSEARCH A/S (DK) | 2010-09-16 | — | — | US | claimed |
| US-20070142450-A1 | Novel urea derivatives and their medical use | NEUROSEARCH A/S (DK) | 2007-06-21 | — | — | US | claimed |
| EP-2255848-A2 | Pharmaceutical combinations of a nicotine receptor modulator and a cognitive enhancer | NeuroSearch AS (DK) | 2010-12-01 | — | — | EP | disclosed |
| US-20070142450-A1 | Novel urea derivatives and their medical use | NEUROSEARCH A/S (DK) | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234349-A1 | PHARMACEUTICAL COMBINATIONS OF A NICOTINE RECEPTOR MODULATOR AND A COGNITIVE ENHANCER | CHRNA10, CHRNA4, CHRNA5 | NTRK1 234/4885CDK19 1979/4885KDR 2590/4885 |
| US-20070142450-A1 | Novel urea derivatives and their medical use | ACHE, NMUR1, NMUR2 | NTRK1 569/4885CDK19 1698/4885KDR 2128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.