Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 6/20 | 0.38 |
| ▸ | TACR1 | P25103 | 6/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3672254 | 0.90 | PTGDR2 (0.42) | PTGDR2LTB4R2TACR1GPBAR1CETP | |
| SCHEMBL3669056 | 0.88 | TACR1 (0.43) | PTGDR2TACR1GPBAR1 | |
| SCHEMBL3670312 | 0.86 | FSHR (0.43) | PTGDR2TACR1GPBAR1CETP | |
| SCHEMBL3670881 | 0.79 | PTGDR2 (0.44) | PTGDR2LTB4R2 | |
| SCHEMBL3671417 | 0.79 | GPBAR1 (0.41) | PTGDR2TACR1GPBAR1CETP | |
| SCHEMBL3669059 | 0.78 | TACR1 (0.43) | PTGDR2TACR1GPBAR1 | |
| SCHEMBL3670884 | 0.77 | PTGDR2 (0.44) | PTGDR2LTB4R2 | |
| SCHEMBL3670313 | 0.77 | FSHR (0.41) | PTGDR2TACR1GPBAR1CETP | |
| SCHEMBL3671389 | 0.76 | TACR1 (0.43) | PTGDR2LTB4R2TACR1GPBAR1 | |
| SCHEMBL1947936 | 0.74 | PTGDR2 (0.61) | PTGDR2LTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240434-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | Ligand Pharmaceuticals Inc. (US) | 2010-10-20 | — | — | EP | claimed |
| WO-2009089192-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | LIGAND PHARMACEUTICALS INC. (US) | 2009-07-16 | — | — | WO | claimed |