Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 9/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 2/20 | 0.35 |
| ▸ | CTSA | P10619 | 2/20 | 0.35 |
| ▸ | CETP | P11597 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | PTGIR | P43119 | 1/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | FSHR | P23945 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3671421 | 0.92 | GPBAR1 (0.41) | GPBAR1PTGDR2TRPM8TACR1CTSA | |
| SCHEMBL3670312 | 0.84 | FSHR (0.43) | GPBAR1PTGDR2TACR1CETPCYP3A4 | |
| SCHEMBL3731304 | 0.81 | CTSA (0.39) | PTGDR2TRPM8CTSA | |
| SCHEMBL3669056 | 0.81 | TACR1 (0.43) | GPBAR1PTGDR2TACR1 | |
| SCHEMBL3731306 | 0.80 | CTSA (0.39) | PTGDR2TRPM8CTSA | |
| SCHEMBL3672250 | 0.79 | PTGDR2 (0.42) | GPBAR1PTGDR2TACR1CETP | |
| SCHEMBL1951055 | 0.78 | PTGDR2 (0.51) | PTGDR2CTSA | |
| SCHEMBL3670313 | 0.75 | FSHR (0.41) | GPBAR1PTGDR2TACR1CETPCYP3A4 | |
| SCHEMBL3669059 | 0.71 | TACR1 (0.43) | GPBAR1PTGDR2TACR1 | |
| SCHEMBL3672254 | 0.70 | PTGDR2 (0.42) | GPBAR1PTGDR2TACR1CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240434-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | Ligand Pharmaceuticals Inc. (US) | 2010-10-20 | — | — | EP | claimed |
| WO-2009089192-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | LIGAND PHARMACEUTICALS INC. (US) | 2009-07-16 | — | — | WO | claimed |