SCHEMBL3672266

SCHEMBL3672266

O=C1NC(=O)c2c1c(Br)c(Br)c1ccccc21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK4 P11802 8/20 0.47
CCND1 P24385 8/20 0.47
CDK5 Q00535 4/20 0.47
CDK5R1 Q15078 4/20 0.47
GSK3B P49841 3/20 0.47
GSK3A P49840 2/20 0.47
CCNE2 O96020 5/20 0.43
CCNE1 P24864 5/20 0.43
CDK2 P24941 5/20 0.43
CCNB2 O95067 4/20 0.43
CDK1 P06493 4/20 0.43
CCNB1 P14635 4/20 0.43
CAMK2B Q13554 4/20 0.43
CAMK2G Q13555 4/20 0.43
CAMK2D Q13557 4/20 0.43
CCNB3 Q8WWL7 4/20 0.43
CAMK2A Q9UQM7 4/20 0.43
PRKACA P17612 2/20 0.43
CCNA2 P20248 2/20 0.43
PRKACG P22612 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11594528 0.82 CDK4 (0.44) CDK4CCND1CDK5CDK5R1GSK3B
SCHEMBL549156 0.82 CDK4 (0.57) CDK4CCND1CDK5CDK5R1GSK3B
SCHEMBL11903054 0.75 CDK4 (0.55) CDK4CCND1CDK5CDK5R1GSK3B
SCHEMBL465112 0.74 CA1 (0.46) GSK3BCASP3
SCHEMBL29470022 0.74 CA1 (0.46) GSK3BCASP3
SCHEMBL11708220 0.73 KDM4E (0.46) CDK4CCND1CDK5CDK5R1GSK3B
SCHEMBL503033 0.72 TSHR (0.58) MAPT
Potassium SCHEMBL11801578 0.71 CA1 (0.43) GSK3B
SCHEMBL11801576 0.71 CA1 (0.43) GSK3B
SCHEMBL11717971 0.71 CASP3 (0.45) MEN1MAPTKMT2APARP1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114188534-B Naphthalene diimide positive electrode material containing sulfur atoms, and preparation method and application thereof 郑州轻工业大学 2024-02-02 CN claimed
CN-113185535-B Benzothiophene compound based on naphthalimide and preparation and application thereof 北京化工大学 2023-01-24 CN claimed
CN-113121563-B Thienophthalimide compound, thiophenethiol and preparation and application thereof 北京化工大学 2022-10-28 CN claimed
CN-113185535-A Benzothiophene compound based on naphthalimide and preparation and application thereof 北京化工大学 2021-07-30 CN claimed
CN-113121563-A Thienophthalimide compound, thiophenethiol and preparation and application thereof 北京化工大学 2021-07-16 CN claimed
US-20070270570-A1 WHITE ELECTROLUMINESCENT POLYMERIC MATERIAL AND PREPARATION THEREOF CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINES ACADEMY OF SCIENCE (CN) 2007-11-22 US claimed
US-20050214568-A1 White electroluminescent polymeric material & preparation thereof CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCE 2005-09-29 US claimed
CN-114188534-B Naphthalene diimide positive electrode material containing sulfur atoms, and preparation method and application thereof 郑州轻工业大学 2024-02-02 CN disclosed
CN-114656474-B Conjugated macrocyclic material based on naphthalimide and preparation method thereof 复旦大学 2023-07-14 CN disclosed
CN-113185535-B Benzothiophene compound based on naphthalimide and preparation and application thereof 北京化工大学 2023-01-24 CN disclosed
CN-113121563-B Thienophthalimide compound, thiophenethiol and preparation and application thereof 北京化工大学 2022-10-28 CN disclosed
CN-114656474-A Conjugated macrocyclic material based on naphthalimide and preparation method thereof 复旦大学 2022-06-24 CN disclosed
CN-113912634-A Bromination method of bilateral bithiophene thick naphthalimide and brominated product 北京化工大学 2022-01-11 CN disclosed
US-20100326527-A1 NAPHTALENE-IMIDE SEMICONDUCTOR POLYMERS BASF SE 2010-12-30 US disclosed
EP-2240529-A1 NAPHTHALENE-IMIDE SEMICONDUCTOR POLYMERS BASF SE (DE) 2010-10-20 EP disclosed
WO-2009098253-A9 NAPHTHALENE-IMIDE SEMICONDUCTOR POLYMERS BASF SE (DE) 2009-10-15 WO disclosed
US-7579091-B2 White electroluminescent polymeric material and preparation thereof CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCE (CN) 2009-08-25 US disclosed
WO-2009098253-A1 NAPHTHALENE-IMIDE SEMICONDUCTOR POLYMERS BASF SE (DE) 2009-08-13 WO disclosed
US-20070270570-A1 WHITE ELECTROLUMINESCENT POLYMERIC MATERIAL AND PREPARATION THEREOF CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINES ACADEMY OF SCIENCE (CN) 2007-11-22 US disclosed
US-20050214568-A1 White electroluminescent polymeric material & preparation thereof CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCE 2005-09-29 US disclosed