SCHEMBL367290

SCHEMBL367290

C[CH]NCC(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6718304 0.75
SCHEMBL2957915 0.75
SCHEMBL6720462 0.73
SCHEMBL26236 0.71
SCHEMBL3123284 0.71
SCHEMBL271293 0.71
SCHEMBL14096414 0.71
SCHEMBL23890456 0.69 ADH1B (0.44)
SCHEMBL6725016 0.69
SCHEMBL639648 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014149486-A1 POLYMERS POLYMERIZED FROM AT LEAST FOUR MONOMERS, AND COMPOSITIONS AND USES THEREOF ISP INVESTMENTS INC. (US) 2014-09-25 WO claimed
US-8119753-B2 Silicone hydrogels with amino surface groups BAUSCH & LOMB INCORPORATED (US) 2012-02-21 US claimed
WO-2012009715-A2 NOVEL CYCLOSPORIN DERIVATIVES FOR THE TREATMENT AND PREVENTION OF A VIRAL INFECTION S&T GLOBAL INC. (US) 2012-01-19 WO claimed
EP-2305637-A2 Substituted tetracycline compounds Paratek Pharmaceuticals, Inc. (US) 2011-04-06 EP claimed
CN-101835846-A Silicone hydrogels with amino surface groups BAUSCH & LOMB 2010-09-15 CN claimed
EP-2207852-A1 SILICONE HYDROGELS WITH AMINO SURFACE GROUPS Bausch & Lomb Incorporated (US) 2010-07-21 EP claimed
US-7612060-B2 Triazoles and methods of use AMGEN INC. (US) 2009-11-03 US claimed
WO-2009055226-A1 SILICONE HYDROGELS WITH AMINO SURFACE GROUPS BAUSCH & LOMB INCORPORATED (US) 2009-04-30 WO claimed
US-20090054460-A1 Piperazine derivatives and methods of use CHEN JIAN J 2009-02-26 US claimed
US-20090048224-A1 COMPOUNDS AND METHODS OF USE AMGEN, INC. (US) 2009-02-19 US claimed
US-20050234044-A1 Cyclic amine derivatives and methods of use AMGEN INC. 2005-10-20 US claimed
WO-2005061467-A2 PIPERAZINE DERIVATIVES AS BRADYKININ ANTAGONISTS AMGEN INC. (US) 2005-07-07 WO claimed
US-20050124654-A1 Compounds and methods of use AMGEN INC. 2005-06-09 US claimed
US-20050014749-A1 analgesics; antiinflammatory agents; antiarthritic agents;Alzheimer's disease; cirrhosis; antiallergens; antihistamines ; anticancer agents; vision defects AMGEN INC. 2005-01-20 US claimed
WO-2004092116-A1 BICYCLIC COMPOUNDS HAVING BRADYKININ RECEPTORS AFFINITY AND PHARMACEUTICAL COMPOSITIONS THEREOF AMGEN, INC. (US) 2004-10-28 WO claimed
WO-2004092164-A1 CYCLIC AMINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF INFLAMMATION-RELATED DISORDERS MEDIATED BY BRADYKININ AMGEN, INC. (US) 2004-10-28 WO claimed
EP-1416933-A1 SUBSTITUTED PIPERIDINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR Amgem, Inc. (US) 2004-05-12 EP claimed
EP-1417190-A1 SUBSTITUTED PIPERAZINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR Amgen Inc. (US) 2004-05-12 EP claimed
WO-2003009847-A1 SUBSTITUTED PIPERIDINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR AMGEM, INC. (US) 2003-02-06 WO claimed
WO-2003009850-A1 SUBSTITUTED PIPERAZINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR AMGEN INC. (US) 2003-02-06 WO claimed