Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.31 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1339747 | 0.77 | NPC1 (0.41) | NPC1RAB9AKMT2ATBXAS1ALDH1A1 | |
| SCHEMBL905574 | 0.77 | NPC1 (0.41) | NPC1RAB9AKMT2ATBXAS1ALDH1A1 | |
| SCHEMBL2321138 | 0.76 | — | — | |
| SCHEMBL538187 | 0.75 | NPC1 (0.39) | NPC1RAB9AKMT2ATBXAS1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL26916942 | 0.74 | NPC1 (0.49) | NPC1RAB9AKMT2ATBXAS1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL26916941 | 0.74 | NPC1 (0.49) | NPC1RAB9AKMT2ATBXAS1ALDH1A1 | |
| SCHEMBL6809047 | 0.74 | NPC1 (0.45) | NPC1RAB9AKMT2ATBXAS1ALDH1A1 | |
| SCHEMBL7574578 | 0.72 | NPC1 (0.46) | NPC1RAB9AKMT2ATBXAS1ALDH1A1 | |
| Toluene SCHEMBL31547896 | 0.71 | NPC1 (0.50) | NPC1RAB9AKMT2AADRA2AADRA2B | |
| SCHEMBL27352543 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2164881-A1 | USE OF SWELLABLE POLYMER FOR SEALING | Evonik Röhm GmbH (DE) | 2010-03-24 | — | — | EP | disclosed |
| WO-2009007154-A1 | USE OF SWELLABLE POLYMER FOR SEALING | EVONIK RÖHM GMBH (DE) | 2009-01-15 | — | — | WO | disclosed |
| EP-0727205-B1 | Thermoplastic coating and binder agent for pharmaceutical forms | ROEHM GMBH (DE) | 2001-05-30 | — | — | EP | disclosed |
| EP-0485840-B2 | Pharmaceutical oral composition and coating agent containing a polysaccharide degradable in the colon | ROEHM GMBH (DE) | 1999-03-03 | — | — | EP | disclosed |
| EP-0727205-A2 | Thermoplastic coating and binder agent for pharmaceutical forms | RÖHM GMBH (DE) | 1996-08-21 | — | — | EP | disclosed |
| EP-0376094-B1 | PROCESS FOR HARDENING AN INJECTION AGENT | RÖHM GMBH (DE) | 1993-06-16 | — | — | EP | disclosed |
| EP-0542159-A1 | Process for treating an aqueous pigment suspension with an aqueous binder agent | RÖHM GMBH (DE) | 1993-05-19 | — | — | EP | disclosed |
| EP-0417570-B1 | AQUEOUS POLYACRYLAT-DISPERSION AS HOT-MELTING ADHESIVE | RÖHM GMBH (DE) | 1993-02-10 | — | — | EP | disclosed |
| EP-0417588-B1 | PROCESS FOR THE PREPARATION OF A COMPLEXED DRUG | RÖHM GMBH (DE) | 1992-08-19 | — | — | EP | disclosed |
| EP-0485840-A2 | Pharmaceutical oral composition and coating agent containing a polysaccharide degradable in the colon | RÖHM GMBH (DE) | 1992-05-20 | — | — | EP | disclosed |
| EP-0417570-A1 | Aqueous polyacrylat-dispersion as hot-melting adhesive | RÖHM GMBH (DE) | 1991-03-20 | — | — | EP | disclosed |
| EP-0417588-A2 | Process for the preparation of a complexed drug | RÖHM GMBH (DE) | 1991-03-20 | — | — | EP | disclosed |
| EP-0376094-A2 | Process for hardening an injection agent | RÖHM GMBH (DE) | 1990-07-04 | — | — | EP | disclosed |