SCHEMBL538187

SCHEMBL538187

C=CC=C(C(=O)O)c1ncc[nH]1

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
KMT2A Q03164 1/20 0.37
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TBXAS1 P24557 2/20 0.32
HTT P42858 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL905574 0.79 NPC1 (0.41) NPC1RAB9AKMT2AKDM4EALDH1A1
SCHEMBL905572 0.79 NPC1 (0.41) NPC1RAB9AKMT2AKDM4EALDH1A1
SCHEMBL1339747 0.79 NPC1 (0.41) NPC1RAB9AKMT2AKDM4EALDH1A1
SCHEMBL3672958 0.75 NPC1 (0.41) NPC1RAB9AKMT2AKDM4EALDH1A1
SCHEMBL7419720 0.73 NPC1 (0.46) NPC1RAB9AKMT2AKDM4EALDH1A1
SCHEMBL262330 0.72
SCHEMBL36523 0.72 NPC1 (0.44) NPC1RAB9AKMT2AKDM4EALDH1A1
SCHEMBL19668747 0.71 NPC1 (0.41) NPC1RAB9AKMT2AKDM4EALDH1A1
SCHEMBL5324109 0.71 NPC1 (0.47) NPC1RAB9AKMT2AKDM4EALDH1A1
SCHEMBL41312 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8148315-B2 Method for uniform deposition of fabric care actives in a non-aqueous fabric treatment system THE PROCTER & GAMBLE COMPANY (US) 2012-04-03 US disclosed
EP-1639075-B1 DELIVERY SYSTEM FOR UNIFORM DEPOSITION OF FABRIC CARE ACTIVES IN A NON-AQUEOUS FABRIC TREATMENT SYSTEM PROCTER & GAMBLE (US) 2012-02-08 EP disclosed
US-7462589-B2 Delivery system for uniform deposition of fabric care actives in a non-aqueous fabric treatment system THE PROCTER & GAMBLE COMPANY (US) 2008-12-09 US disclosed
US-7300593-B2 Process for purifying a lipophilic fluid THE PROCTER & GAMBLE COMPANY (US) 2007-11-27 US disclosed
US-7300594-B2 Process for purifying a lipophilic fluid by modifying the contaminants THE PROCTER & GAMBLE COMPANY (US) 2007-11-27 US disclosed
US-7053033-B2 Treatment of fabric articles with specific fabric care actives and a siloxane lipophilic fluid PROCTER & GAMBLE COMPANY (US) 2006-05-30 US disclosed
EP-1639190-A1 PROCESS FOR PURIFYING A LIPOPHILIC FLUID THE PROCTER & GAMBLE COMPANY (US) 2006-03-29 EP disclosed
EP-1639188-A1 PROCESS FOR PURIFYING A LIPOPHILIC FLUID BY MODIFYING THE CONTAMINANTS THE PROCTER & GAMBLE COMPANY (US) 2006-03-29 EP disclosed
EP-1639075-A1 DELIVERY SYSTEM FOR UNIFORM DEPOSITION OF FABRIC CARE ACTIVES IN A NON-AQUEOUS FABRIC TREATMENT SYSTEM THE PROCTER & GAMBLE COMPANY (US) 2006-03-29 EP disclosed
EP-1639076-A1 METHOD FOR UNIFORM DEPOSITION OF FABRIC CARE ACTIVES IN A NON-AQUEOUS FABRIC TREATMENT SYSTEM THE PROCTER & GAMBLE COMPANY (US) 2006-03-29 EP disclosed
WO-2005003442-A1 PROCESS FOR PURIFYING A LIPOPHILIC FLUID THE PROCTER & GAMBLE COMPANY (US) 2005-01-13 WO disclosed
US-20050009724-A1 Process for purifying a lipophilic fluid THE PROCTER & GAMBLE COMPANY 2005-01-13 US disclosed
US-20050000027-A1 Delivery system for uniform deposition of fabric care actives in a non-aqueous fabric treatment system PROCTER & GAMBLE COMPANY, THE 2005-01-06 US disclosed
US-20050000029-A1 Process for purifying a lipophilic fluid by modifying the contaminants THE PROCTER & GAMBLE COMPANY 2005-01-06 US disclosed
US-20050000028-A1 Method for uniform deposition of fabric care actives in a non-aqueous fabric treatment system PROCTER & GAMBLE COMPANY, THE 2005-01-06 US disclosed
EP-1463857-A1 TREATMENT OF FABRIC ARTICLES WITH SPECIFIC FABRIC CARE ACTIVES THE PROCTER & GAMBLE COMPANY (US) 2004-10-06 EP disclosed
US-20040142839-A1 TREATMENT OF FABRIC ARTICLES WITH SPECIFIC FABRIC CARE ACTIVES THE PROCTER & GAMBLE COMPANY 2004-07-22 US disclosed
US-6734153-B2 APPLYING LIPOPHILIC FLUID TO FABRICS PROCTER & GAMBLE COMPANY 2004-05-11 US disclosed
WO-2003054281-A1 TREATMENT OF FABRIC ARTICLES WITH SPECIFIC FABRIC CARE ACTIVES THE PROCTER & GAMBLE COMPANY (US) 2003-07-03 WO disclosed
US-20030119709-A1 Treatment of fabric articles with specific fabric care actives THE PROCTER & GAMBLE COMAPANY 2003-06-26 US disclosed