Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.49 |
| ▸ | USP2 | O75604 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | RGS12 | O14924 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | CASP7 | P55210 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28552747 | 0.87 | MEN1 (0.55) | KMT2AMEN1POLBUSP2MAPT | |
| SCHEMBL27649471 | 0.87 | MEN1 (0.53) | KMT2AMEN1POLBUSP2MAPT | |
| Butane SCHEMBL11876142 | 0.84 | MEN1 (0.65) | KMT2AMEN1POLBUSP2MAPT | |
| SCHEMBL17529462 | 0.83 | MEN1 (0.53) | KMT2AMEN1POLBUSP2MAPT | |
| SCHEMBL28495677 | 0.83 | MEN1 (0.60) | KMT2AMEN1POLBUSP2MAPT | |
| SCHEMBL5517131 | 0.82 | MEN1 (0.51) | KMT2AMEN1POLBUSP2MAPT | |
| SCHEMBL17529464 | 0.81 | FGFR1 (0.53) | KMT2AMEN1POLBUSP2MAPT | |
| Hydrochloric Acid SCHEMBL16213593 | 0.80 | FGFR1 (0.52) | KMT2AMEN1POLBUSP2MAPT | |
| SCHEMBL19001472 | 0.79 | FGFR1 (0.51) | KMT2AMEN1POLBUSP2MAPT | |
| Hydrochloric Acid SCHEMBL16213631 | 0.78 | FGFR1 (0.50) | KMT2AMEN1POLBUSP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210322173-A1 | CRAFTING OF CARTILAGE | LIFENET HEALTH (US) | 2021-10-21 | — | — | US | disclosed |
| US-11147674-B2 | Crafting of cartilage | LIFENET HEALTH (US) | 2021-10-19 | — | — | US | disclosed |
| US-20210315703-A1 | IMPLANTATION OF CARTILAGE | LIFENET HEALTH (US) | 2021-10-14 | — | — | US | disclosed |
| US-10881515-B2 | Implantation of cartilage | LIFENET HEALTH (US) | 2021-01-05 | — | — | US | disclosed |
| US-20180104062-A1 | CRAFTING OF CARTILAGE | TRUIST BANK | 2018-04-19 | — | — | US | disclosed |
| US-9744043-B2 | Crafting of cartilage | LIFENET HEALTH (US) | 2017-08-29 | — | — | US | disclosed |
| US-9125743-B2 | Devitalization and recellularization of cartilage | LIFENET HEALTH (US) | 2015-09-08 | — | — | US | disclosed |
| US-20130030528-A1 | Implantation of Cartilage | LIFENET HEALTH (US) | 2013-01-31 | — | — | US | disclosed |
| EP-2178460-A2 | CARTILAGE GRAFTS | Lifenet Health (US) | 2010-04-28 | — | — | EP | disclosed |
| US-20090024224-A1 | Implantation of cartilage | LIFENET HEALTH | 2009-01-22 | — | — | US | disclosed |
| WO-2009011849-A2 | CARTILAGE GRAFTS | LIFENET HEALTH (US) | 2009-01-22 | — | — | WO | disclosed |
| US-20090024223-A1 | Crafting of cartilage | TRUIST BANK | 2009-01-22 | — | — | US | disclosed |
| US-20090024229-A1 | Devitalization and recellularization of cartilage | TRUIST BANK | 2009-01-22 | — | — | US | disclosed |
| US-20080077251-A1 | free from bone marrow; a graft suitable for recellularizing in vitro, in vivo, or in situ; soaking in cleaning solution optionally conducted under sonication; repairing a cartilage defect and implanting a cartilage graft; A repaired cartilage defect claimed | TRUIST BANK | 2008-03-27 | — | — | US | disclosed |