Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.30 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL28334184 | 0.82 | ALDH1A1 (0.42) | CYP2C9SMN1; SMN2ALDH1A1GAATSHR | |
| Styrene SCHEMBL8068589 | 0.77 | AKR1C3 (0.52) | CYP2C9SMN1; SMN2ALDH1A1TSHRAKR1C3 | |
| Styrene SCHEMBL293504 | 0.77 | AKR1C3 (0.52) | CYP2C9SMN1; SMN2ALDH1A1TSHRAKR1C3 | |
| SCHEMBL29558930 | 0.76 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1GAATSHRTP53 | |
| SCHEMBL81306 | 0.76 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1GAATSHRTP53 | |
| Styrene SCHEMBL3665393 | 0.75 | AKR1C3 (0.49) | CYP2C9SMN1; SMN2ALDH1A1TSHRAKR1C3 | |
| Styrene SCHEMBL9879337 | 0.75 | AKR1C3 (0.49) | CYP2C9SMN1; SMN2ALDH1A1TSHRAKR1C3 | |
| SCHEMBL28237248 | 0.75 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1GAATSHRTP53 | |
| Hydrochloric Acid SCHEMBL9225051 | 0.75 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1GAATSHRTP53 | |
| SCHEMBL31297142 | 0.74 | AKR1C3 (0.43) | CYP2C9ALDH1A1TSHRAKR1C3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966296-B1 | POLYCARBONATE MOULDING COMPOSITIONS | BAYER MATERIALSCIENCE AG (DE) | 2010-06-23 | — | — | EP | disclosed |
| EP-1966296-A1 | POLYCARBONATE MOULDING COMPOSITIONS | Bayer MaterialScience AG (DE) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007068384-A1 | POLYCARBONATE MOULDING COMPOSITIONS | BAYER MATERIALSCIENCE AG (DE) | 2007-06-21 | — | — | WO | disclosed |