Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.51 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 3/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL15903300 | 0.98 | KDM4E (0.54) | KDM4EALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL6947877 | 0.90 | CYP2A6 (0.46) | KDM4EALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL31217406 | 0.82 | KDM4E (0.49) | KDM4EALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL5472936 | 0.82 | KDM4E (0.41) | KDM4EALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL1567503 | 0.81 | ACHE (0.58) | KDM4EALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL29850498 | 0.81 | ACHE (0.58) | KDM4EALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL30437408 | 0.81 | KDM4E (0.51) | KDM4EALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL19899145 | 0.80 | KDM4E (0.64) | KDM4EALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL30661168 | 0.80 | KDM4E (0.64) | KDM4EALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL10711625 | 0.80 | KDM4E (0.50) | KDM4EALDH1A1MAPTTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114436790-B | Synthesis method of 6-methoxy-1-tetralone | 浙江仙居君业药业有限公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-114591727-A | Organic long-afterglow luminescent material, preparation and application | 中国科学院上海有机化学研究所 | 2022-06-07 | — | — | CN | disclosed |
| CN-114436790-A | Synthesis method of 6-methoxy-1-tetralone | 浙江仙居君业药业有限公司 | 2022-05-06 | — | — | CN | disclosed |
| US-10259794-B2 | Methods for preparing fused bicyclic 2, 4-diaminopyrimidine derivatives | CEPHALON, INC. (US) | 2019-04-16 | — | — | US | disclosed |
| EP-3237408-B1 | METHODS FOR PREPARING FUSED BICYCLIC 2, 4-DIAMINOPYRIMIDINE DERIVATIVES | CEPHALON INC (US) | 2018-10-31 | — | — | EP | disclosed |
| US-20170369451-A1 | METHODS FOR PREPARING FUSED BICYCLIC 2, 4-DIAMINOPYRIMIDINE DERIVATIVES | CEPHALON, INC. | 2017-12-28 | — | — | US | disclosed |
| CN-107434813-A | Display | 诺瓦尔德股份有限公司 | 2017-12-05 | — | — | CN | disclosed |
| EP-3237408-A1 | METHODS FOR PREPARING FUSED BICYCLIC 2, 4-DIAMINOPYRIMIDINE DERIVATIVES | Cephalon, Inc. (US) | 2017-11-01 | — | — | EP | disclosed |
| CN-104247070-B | Display device | 诺瓦尔德股份有限公司 | 2017-04-12 | — | — | CN | disclosed |
| WO-2016105529-A1 | METHODS FOR PREPARING FUSED BICYCLIC 2, 4-DIAMINOPYRIMIDINE DERIVATIVES | CEPHALON, INC. (US) | 2016-06-30 | — | — | WO | disclosed |
| EP-0256849-A1 | Aromatization process | ETHYL CORPORATION (US) | 1988-02-24 | — | — | EP | disclosed |
| CN-87104970-A | The amino-5,6,7 that replaces, 8-tetralyl oxo acetate its preparation method and as the purposes of medicine | — | 1988-02-03 | — | — | CN | disclosed |
| EP-0179855-A4 | DOPAMINE AGONISTS. | NELSON RES & DEV COMPANY (US) | 1986-08-21 | — | — | EP | disclosed |
| EP-0179855-A1 | DOPAMINE AGONISTS. | NELSON RES & DEV (US) | 1986-05-07 | — | — | EP | disclosed |
| WO-1985004582-A1 | NOVEL DOPAMINE AGONISTS | NELSON RESEARCH AND DEVELOPMENT COMPANY (US) | 1985-10-24 | — | — | WO | disclosed |
| EP-0150192-A4 | BICYCLIC BENZENOID AMINOALKYLENE ETHERS AND THIOETHERS. | RORER INTERNAT OVERSEAS INC (US) | 1985-09-16 | — | — | EP | disclosed |
| US-4540691-A | Dopamine agonists and use thereof | NELSON RESEARCH & DEVELOPMENT CO. (US) | 1985-09-10 | — | — | US | disclosed |
| EP-0150192-A1 | BICYCLIC BENZENOID AMINOALKYLENE ETHERS AND THIOETHERS. | RORER INT OVERSEAS (US) | 1985-08-07 | — | — | EP | disclosed |
| WO-1984004247-A1 | BICYCLIC BENZENOID AMINOALKYLENE ETHERS AND THIOETHERS, AND THEIR PHARMACEUTICAL USES | RORER INT OVERSEAS (US) | 1984-11-08 | — | — | WO | disclosed |
| EP-0106486-A2 | Improvements in or relating to novel octahydrobenz(f)isoquinolines | ELI LILLY AND COMPANY (US) | 1984-04-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170369451-A1 | METHODS FOR PREPARING FUSED BICYCLIC 2, 4-DIAMINOPYRIMIDINE DERIVATIVES | DPYD, LIG4, CEP170 | KDM4E 353/4885ALDH1A1 1904/4885MAPT 2618/4885 |
| US-10259794-B2 | Methods for preparing fused bicyclic 2, 4-diaminopyrimidine derivatives | DPYD, LIG4, CEP170 | KDM4E 353/4885ALDH1A1 1904/4885MAPT 2618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.