Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 20/20 | 0.54 |
| ▸ | PTGER3 | P43115 | 7/20 | 0.54 |
| ▸ | PTGER2 | P43116 | 6/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3674649 | 1.00 | PTGER4 (0.54) | PTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL3671539 | 1.00 | PTGER4 (0.54) | PTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL11024470 | 1.00 | PTGER4 (0.54) | PTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL3677438 | 1.00 | PTGER4 (0.54) | PTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL3680384 | 1.00 | PTGER4 (0.54) | PTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL3682609 | 1.00 | PTGER4 (0.54) | PTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL11024464 | 1.00 | PTGER4 (0.54) | PTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL5902919 | 0.87 | PTGER4 (0.39) | PTGER4PTGER3PTGER2 | |
| SCHEMBL16089510 | 0.87 | PTGER4 (0.54) | PTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL5902684 | 0.87 | PTGER4 (0.41) | PTGER4PTGER3PTGER2PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109010929-B | Medical catheter | 湖南博隽生物医药有限公司 | 2021-08-13 | — | — | CN | claimed |
| CN-112142914-A | Antibacterial fluorosilicone material copolymer and application thereof | 湖南博隽生物医药有限公司 | 2020-12-29 | — | — | CN | claimed |
| CN-112057675-A | Preparation method of biocompatible catheter | 湖南博隽生物医药有限公司 | 2020-12-11 | — | — | CN | claimed |
| CN-112043940-A | Bacteriostatic hydrophilic catheter | 湖南博隽生物医药有限公司 | 2020-12-08 | — | — | CN | claimed |
| CN-110804359-A | Environment-friendly water-based paint and preparation method thereof | 孙爱芬 | 2020-02-18 | — | — | CN | claimed |
| US-20130317013-A1 | EP4 RECEPTOR AGONIST, COMPOSITIONS AND METHODS THEREOF | BILLOT XAVIER (CA) | 2013-11-28 | — | — | US | claimed |
| EP-1513589-B1 | 1,5-DISUBSTITUTED PYRROLID-2-ONE DERIVATIVES FOR USE AS EP4 RECEPTOR AGONISTS IN THE TREATMENT OF EYE DISEASES SUCH AS GLAUCOMA | MERCK FROSST CANADA LTD (CA) | 2010-11-10 | — | — | EP | claimed |
| US-20090258918-A1 | EP4 receptor agonist, compositions and methods thereof | BILLOT XAVIER | 2009-10-15 | — | — | US | claimed |
| US-20050239872-A1 | 1,5-distributed pyrrolid-2-one derivatives for use as ep4 receptor agonists in the teatment of eye diseases such as glaucoma | MERCK FROSST CANADA LTD. (CA) | 2005-10-27 | — | — | US | claimed |
| CN-109010929-B | Medical catheter | 湖南博隽生物医药有限公司 | 2021-08-13 | — | — | CN | disclosed |
| CN-112142914-A | Antibacterial fluorosilicone material copolymer and application thereof | 湖南博隽生物医药有限公司 | 2020-12-29 | — | — | CN | disclosed |
| CN-112057675-A | Preparation method of biocompatible catheter | 湖南博隽生物医药有限公司 | 2020-12-11 | — | — | CN | disclosed |
| CN-112043940-A | Bacteriostatic hydrophilic catheter | 湖南博隽生物医药有限公司 | 2020-12-08 | — | — | CN | disclosed |
| CN-110804359-A | Environment-friendly water-based paint and preparation method thereof | 孙爱芬 | 2020-02-18 | — | — | CN | disclosed |
| US-20090258918-A1 | EP4 receptor agonist, compositions and methods thereof | BILLOT XAVIER | 2009-10-15 | — | — | US | disclosed |
| US-20090258918-A1 | EP4 receptor agonist, compositions and methods thereof | BILLOT XAVIER | 2009-10-15 | — | — | US | disclosed |
| US-20090258918-A1 | EP4 receptor agonist, compositions and methods thereof | BILLOT XAVIER | 2009-10-15 | — | — | US | disclosed |
| US-20050239872-A1 | 1,5-distributed pyrrolid-2-one derivatives for use as ep4 receptor agonists in the teatment of eye diseases such as glaucoma | MERCK FROSST CANADA LTD. (CA) | 2005-10-27 | — | — | US | disclosed |
| EP-1513589-A1 | 1,5-DISUBSTITUTED PYRROLID-2-ONE DERIVATIVES FOR USE AS EP4 RECEPTOR AGONISTS IN THE TREATMENT OF EYE DISEASES SUCH AS GLAUCOMA | MERCK FROSST CANADA INC. (CA) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003103772-A1 | 1,5-DISTRIBUTED PYRROLID-2-ONE DERIVATIVES FOR USE AS EP4 RECEPTOR AGONISTS IN THE TEATMENT OF EYE DISEASES SUCH AS GLAUCOMA | MERCK FROSST CANADA & CO. (CA) | 2003-12-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239872-A1 | 1,5-distributed pyrrolid-2-one derivatives for use as ep4 receptor agonists in the teatment of eye diseases such as glaucoma | PTGER1, PTGER4, PTGER2 | PTGER4 2/4885PTGER3 4/4885PTGER2 3/4885 |
| US-20090258918-A1 | EP4 receptor agonist, compositions and methods thereof | PTGER4, PTGER1, PTGER3 | PTGER4 1/4885PTGER3 3/4885PTGER2 4/4885 |
| US-20130317013-A1 | EP4 RECEPTOR AGONIST, COMPOSITIONS AND METHODS THEREOF | PTGER4, PTGER1, PTGER3 | PTGER4 1/4885PTGER3 3/4885PTGER2 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.