SCHEMBL11024464

SCHEMBL11024464

O=C1CCC(/C=C/C(O)C(F)(F)c2ccccc2)N1CCCCCCc1nnn[nH]1

nearest known ligand 0.54

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 20/20 0.54
PTGER3 P43115 7/20 0.54
PTGER2 P43116 6/20 0.49
PTGER1 P34995 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3674649 1.00 PTGER4 (0.54) PTGER4PTGER3PTGER2PTGER1
SCHEMBL3671539 1.00 PTGER4 (0.54) PTGER4PTGER3PTGER2PTGER1
SCHEMBL11024470 1.00 PTGER4 (0.54) PTGER4PTGER3PTGER2PTGER1
SCHEMBL3677438 1.00 PTGER4 (0.54) PTGER4PTGER3PTGER2PTGER1
SCHEMBL3680384 1.00 PTGER4 (0.54) PTGER4PTGER3PTGER2PTGER1
SCHEMBL3673657 1.00 PTGER4 (0.54) PTGER4PTGER3PTGER2PTGER1
SCHEMBL3682609 1.00 PTGER4 (0.54) PTGER4PTGER3PTGER2PTGER1
SCHEMBL5902919 0.87 PTGER4 (0.39) PTGER4PTGER3PTGER2
SCHEMBL16089510 0.87 PTGER4 (0.54) PTGER4PTGER3PTGER2PTGER1
SCHEMBL5902684 0.87 PTGER4 (0.41) PTGER4PTGER3PTGER2PTGER1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015109112-A1 COMBINATION TREATMENT OF ANTIBIOTIC AND GPCR AGONIST FOR VIRAL/BACTERIAL CO-INFECTIONS GEMMUS PHARMA INC. (US) 2015-07-23 WO claimed
WO-2015109112-A1 COMBINATION TREATMENT OF ANTIBIOTIC AND GPCR AGONIST FOR VIRAL/BACTERIAL CO-INFECTIONS GEMMUS PHARMA INC. (US) 2015-07-23 WO disclosed
US-20150196578-A1 COMBINATION THERAPY TREATMENT FOR VIRAL INFECTIONS GEMMUS PHARMA INC (US) 2015-07-16 US disclosed
US-20120190637-A1 COMBINATION THERAPY TREATMENT FOR VIRAL INFECTIONS GEMMUS PHARMA, INC. (US) 2012-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150196578-A1 COMBINATION THERAPY TREATMENT FOR VIRAL INFECTIONS PTGER4, TMPRSS4, GPR4 PTGER4 1/4885PTGER3 15/4885PTGER2 27/4885
US-20120190637-A1 COMBINATION THERAPY TREATMENT FOR VIRAL INFECTIONS PTGER4, TMPRSS4, GPR4 PTGER4 1/4885PTGER3 15/4885PTGER2 27/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.