Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 5/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL573141 | 0.76 | — | — | |
| SCHEMBL305484 | 0.76 | — | — | |
| SCHEMBL19834168 | 0.75 | KDM4E (0.32) | — | |
| SCHEMBL7934532 | 0.75 | TSHR (0.46) | TSHRATM | |
| SCHEMBL7934533 | 0.75 | TSHR (0.46) | TSHRATM | |
| SCHEMBL28293096 | 0.74 | TSHR (0.36) | PRKCATSHR | |
| SCHEMBL3674540 | 0.73 | TSHR (0.32) | TSHRATM | |
| SCHEMBL2868662 | 0.73 | KDM4E (0.43) | TSHRATM | |
| SCHEMBL27293911 | 0.73 | TSHR (0.39) | PRKCATSHRATM | |
| SCHEMBL11811024 | 0.73 | KDM4E (0.43) | TSHRATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1890171-B1 | Wettable hydrogels comprising reactive, hydrophilic, polymeric internal wetting agents | JOHNSON & JOHNSON VISION CARE (US) | 2010-12-22 | — | — | EP | claimed |
| EP-1890171-A2 | Wettable hydrogels comprising reactive, hydrophilic, polymeric internal wetting agents | Johnson & Johnson Vision Care, Inc. (US) | 2008-02-20 | — | — | EP | claimed |