Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL755514 | 0.90 | HCAR2 (0.31) | HCAR2ATM | |
| SCHEMBL755619 | 0.80 | TSHR (0.40) | TSHR | |
| SCHEMBL755620 | 0.78 | — | — | |
| SCHEMBL9301363 | 0.75 | TSHR (0.37) | TSHRATM | |
| SCHEMBL182380 | 0.73 | ATM (0.54) | TSHRHCAR2ATM | |
| SCHEMBL182378 | 0.73 | ATM (0.54) | TSHRHCAR2ATM | |
| SCHEMBL3673668 | 0.73 | PRKCA (0.35) | TSHRATM | |
| SCHEMBL1718931 | 0.71 | ATM (0.44) | TSHRHCAR2ATM | |
| SCHEMBL759922 | 0.71 | TSHR (0.36) | TSHR | |
| SCHEMBL395579 | 0.70 | ATM (0.43) | TSHRHCAR2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1809344-B1 | BIOMEDICAL DEVICES CONTAINING AMPHIPHILIC BLOCK COPOLYMERS | JOHNSON & JOHNSON VISION CARE (US) | 2010-01-20 | — | — | EP | claimed |