SCHEMBL367457

SCHEMBL367457

CC1C(=O)NC(=O)NC1=O

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
HSD17B10 Q99714 2/20 0.39
LMNA P02545 3/20 0.37
KDM4E B2RXH2 3/20 0.35
OGT O15294 1/20 0.35
USP2 O75604 1/20 0.35
MAPT P10636 1/20 0.35
RECQL P46063 1/20 0.35
BLM P54132 1/20 0.35
CRBN Q96SW2 1/20 0.35
BRPF1 P55201 1/20 0.31
CREBBP Q92793 1/20 0.31
RGS12 O14924 1/20 0.30
ALDH1A1 P00352 1/20 0.30
GLA P06280 1/20 0.30
GAA P10253 1/20 0.30
BACE1 P56817 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17294184 0.97 TSHR (0.50) TSHRHSD17B10LMNAKDM4EOGT
SCHEMBL18342514 0.86
SCHEMBL10289564 0.81 TSHR (0.42) TSHRHSD17B10LMNA
SCHEMBL9803807 0.75 ALDH1A1 (0.46) TSHRKDM4EMAPTCRBNALDH1A1
SCHEMBL14169780 0.69 CREBBP (0.65) KDM4EMAPTBRPF1CREBBPALDH1A1
SCHEMBL6100849 0.69
SCHEMBL8110002 0.69
SCHEMBL21767 0.69
SCHEMBL642543 0.67 TSHR (0.40) TSHRHSD17B10LMNAKDM4EOGT
SCHEMBL145905 0.67 TSHR (0.46) TSHRHSD17B10LMNAKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 524 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118652507-B Ultraviolet-proof polyvinyl chloride solid medicinal hard tablet and preparation method thereof 深圳市天利兴科技开发有限公司 2025-04-01 CN claimed
CN-106267314-A A kind of preparation method of antibacterial corrosion-resistant bearing hydrocolloid dressing 常州亚环环保科技有限公司 2017-01-04 CN claimed
CN-101734036-B Positive thermosensitive CTP plate adopting active etherate in condensation resin of pyrogallol and divinylbenzene and preparation method thereof TAIXING CITY ORIENT IND COMPANY 2013-06-19 CN claimed
CN-101734034-B High sensitivity positive thermosensitive CTP plate and preparation method thereof TAIXING CITY ORIENT IND COMPANY 2012-09-19 CN claimed
CN-101734035-B Positive thermosensitive CTP plate and preparation method thereof TAIXING CITY ORIENT IND COMPANY 2012-05-23 CN claimed
CN-101930172-B Thermosensitive CTP thermal imaging liquid taking active etherate of pyrogallol and divinylbenzene polycondensation resin as dissolution inhibitor TAIXING CITY ORIENT IND COMPANY 2012-05-09 CN claimed
CN-101762976-B Active etherate of pyrogallol acetonide resin as heat-sensitive CTP thermo-sensitive imaging liquid of dissolution inhibitor UNIV BEIJING NORMAL 2012-01-11 CN claimed
CN-101762975-B Thermosensitive cytidine triphosphate (CTP) sensible-heat imaging solution of barbituric acid compound as additive TAIXING CITY ORIENT INDUSTRIAL COMPANY (CN) 2011-12-07 CN claimed
CN-101930172-A Thermosensitive CTP thermal-induction imaging liquid taking active etherate of pyrogallol and divinylbenzene polycondensate resin as dissolution inhibitor TAIXING CITY ORIENT IND COMPANY 2010-12-29 CN claimed
CN-101762975-A Thermosensitive cytidine triphosphate (CTP) sensible-heat imaging solution of barbituric acid compound as additive UNIV BEIJING NORMAL 2010-06-30 CN claimed
EP-0623133-A4 SUBSTITUTED AMINO ALKYL COMPOUNDS. CELL THERAPEUTICS INC (US) 1995-10-11 EP claimed
EP-0662834-A1 NOVEL EPOXIDE-CONTAINING COMPOUNDS CELL THERAPEUTICS, INC. (US) 1995-07-19 EP claimed
WO-1994022863-A9 SECOND MESSENGER CELL SIGNALING INHIBITORS 1994-12-22 WO claimed
EP-0623133-A1 SUBSTITUTED AMINO ALKYL COMPOUNDS CELL THERAPEUTICS, INC. (US) 1994-11-09 EP claimed
WO-1994024133-A1 RING-SUBSTITUTED CELL SIGNALING INHIBITORS CELL THERAPEUTICS, INC. (US) 1994-10-27 WO claimed
WO-1994022449-A1 THERAPEUTIC COMPOUNDS CELL THERAPEUTICS, INC. (US) 1994-10-13 WO claimed
WO-1994022863-A1 SECOND MESSENGER CELL SIGNALING INHIBITORS CELL THERAPEUTICS, INC. (US) 1994-10-13 WO claimed
WO-1994015606-A1 OLEFIN-SUBSTITUTED LONG CHAIN COMPOUNDS CELL THERAPEUTICS, INC. (US) 1994-07-21 WO claimed
WO-1994011370-A1 SUBSTITUTED AMINO ALKYL COMPOUNDS CELL THERAPEUTICS, INC. (US) 1994-05-26 WO claimed
WO-1994006431-A1 NOVEL EPOXIDE-CONTAINING COMPOUNDS CELL THERAPEUTICS, INC. (US) 1994-03-31 WO claimed