Ascorbic Acid

Ascorbic Acid

SCHEMBL3674599

CCOC(C)OCC.O=C1O[C@H]([C@@H](O)CO)C(O)=C1O

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.71
MAPT P10636 2/20 0.71
L3MBTL1 Q9Y468 1/20 0.71
HSPD1 P10809 1/20 0.50
HSPE1 P61604 1/20 0.50
TST Q16762 1/20 0.50
RECQL P46063 1/20 0.50
BLM P54132 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
TYR P14679 2/20 0.39
MANBA O00462 1/20 0.33
THRB P10828 1/20 0.33
HIF1A Q16665 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ascorbic Acid SCHEMBL325827 0.87 MAPT (0.78) LMNAMAPTL3MBTL1HSPD1HSPE1
Ascorbic Acid SCHEMBL28456797 0.87 MAPT (0.78) LMNAMAPTL3MBTL1HSPD1HSPE1
Ascorbic Acid SCHEMBL1533996 0.86 MAPT (0.89) LMNAMAPTL3MBTL1HSPD1HSPE1
Ascorbic Acid SCHEMBL17888786 0.85 MAPT (0.86) LMNAMAPTL3MBTL1HSPD1HSPE1
Ascorbic Acid SCHEMBL30327382 0.85 MAPT (0.86) LMNAMAPTL3MBTL1HSPD1HSPE1
Ascorbic Acid SCHEMBL31487361 0.85 MAPT (0.86) LMNAMAPTL3MBTL1HSPD1HSPE1
Ascorbic Acid SCHEMBL15577247 0.85 MAPT (0.93) LMNAMAPTL3MBTL1HSPD1HSPE1
Ascorbic Acid SCHEMBL27955458 0.85 MAPT (0.93) LMNAMAPTL3MBTL1HSPD1HSPE1
Ascorbic Acid SCHEMBL28240604 0.85 MAPT (0.93) LMNAMAPTL3MBTL1HSPD1HSPE1
Ascorbic Acid SCHEMBL10957988 0.84 MAPT (1.00) LMNAMAPTL3MBTL1HSPD1HSPE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8702813-B2 Use of ascorbic acid derivatives for dyeing keratin-containing fibres MERCK PATENT GMBH (DE) 2014-04-22 US disclosed
US-20130228192-A1 USE OF ASCORBIC ACID DERIVATIVES FOR DYEING KERATIN-CONTAINING FIBRES MERCK PATENT GMBH (DE) 2013-09-05 US disclosed
EP-1621582-B1 RESIN COMPOSITION AND PROCESS FOR PRODUCING THE SAME KANEKA CORP (JP) 2012-10-31 EP disclosed
US-7838586-B2 Resin composition and process for producing the same KANEKA CORPORATION (JP) 2010-11-23 US disclosed
US-20060211799-A1 Resin composition and process for producing the same KANEKA CORPORATION (JP) 2006-09-21 US disclosed
EP-1621582-A1 RESIN COMPOSITION AND PROCESS FOR PRODUCING THE SAME KANEKA CORPORATION (JP) 2006-02-01 EP disclosed
EP-1104415-A1 METHOD OF MANUFACTURE OF 1,3-OXATHIOLANE NUCLEOSIDES Triangle Pharmaceuticals Inc. (US) 2001-06-06 EP disclosed
WO-2000009494-A1 METHOD OF MANUFACTURE OF 1,3-OXATHIOLANE NUCLEOSIDES TRIANGLE PHARMACEUTICALS, INC. (US) 2000-02-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130228192-A1 USE OF ASCORBIC ACID DERIVATIVES FOR DYEING KERATIN-CONTAINING FIBRES KRT18, PROC, DSG1 LMNA 310/4885MAPT 313/4885L3MBTL1 4880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.