SCHEMBL367480

SCHEMBL367480

C(=Cc1ccccc1)OOOC=Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.50
TRPA1 O75762 3/20 0.43
NFE2L2 Q16236 3/20 0.42
ALDH1A1 P00352 2/20 0.42
LMNA P02545 2/20 0.42
CYP19A1 P11511 1/20 0.42
MAOA P21397 1/20 0.42
ALOX5 P09917 1/20 0.42
MAPK1 P28482 1/20 0.42
IDO1 P14902 2/20 0.41
HDAC3 O15379 1/20 0.41
TNKS O95271 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HCAR2 Q8TDS4 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41
HDAC8 Q9BY41 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL367479 1.00 MAOB (0.50) MAOBTRPA1NFE2L2ALDH1A1LMNA
SCHEMBL367481 0.89 MAOB (0.55) MAOBTRPA1NFE2L2ALDH1A1LMNA
SCHEMBL13842310 0.80 TRPA1 (0.50) MAOBTRPA1NFE2L2ALDH1A1CYP1A2
SCHEMBL175339 0.78 MAOB (0.55) MAOBTRPA1NFE2L2ALDH1A1LMNA
SCHEMBL175340 0.78 MAOB (0.55) MAOBTRPA1NFE2L2ALDH1A1LMNA
SCHEMBL31016004 0.75 MAOB (0.41) MAOBTRPA1NFE2L2ALDH1A1MAPK1
SCHEMBL15709852 0.74 MAOB (0.50) MAOBTRPA1NFE2L2ALDH1A1LMNA
SCHEMBL11314805 0.74 IDO1 (0.52) MAOBTRPA1NFE2L2ALDH1A1LMNA
SCHEMBL3625300 0.74 MAOB (0.50) MAOBTRPA1NFE2L2ALDH1A1LMNA
SCHEMBL14681134 0.74 TRPA1 (0.54) MAOBTRPA1NFE2L2ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130292043-A1 HIGH PERFORMANCE BALLOON CATHETER/COMPONENT BOSTON SCIENT SCIMED INC (US) 2013-11-07 US disclosed
US-8481139-B2 High performance balloon catheter/component BOSTON SCIENTIFIC SCIMED, INC. (US) 2013-07-09 US disclosed
EP-1646486-B1 Process for preparing medical devices BOSTON SCIENT LTD (BB) 2012-02-22 EP disclosed
US-20120013043-A1 MEDICAL DEVICES AND PROCESSES FOR PREPARING SAME BOSTON SCIENTIFIC SCIMED, INC. (US) 2012-01-19 US disclosed
US-8025637-B2 Medical balloons and processes for preparing same BOSTON SCIENTIFIC SCIMED, INC. (US) 2011-09-27 US disclosed
US-20100094213-A1 HIGH PERFORMANCE BALLOON CATHETER/COMPONENT BOSTON SCIENTIFIC SCIMED, INC. (US) 2010-04-15 US disclosed
US-7635510-B2 High performance balloon catheter/component BOSTON SCIENTIFIC SCIMED, INC. (US) 2009-12-22 US disclosed
EP-1773423-B1 HIGH PERFORMANCE BALLOON CATHETER/COMPONENT BOSTON SCIENT LTD (BB) 2009-09-30 EP disclosed
EP-1773423-A1 HIGH PERFORMANCE BALLOON CATHETER/COMPONENT Boston Scientific Limited (BB) 2007-04-18 EP disclosed
EP-1646486-A2 MEDICAL DEVICES AND PROCESSES FOR PREPARING SAME Boston Scientific Limited (BB) 2006-04-19 EP disclosed
WO-2006016934-A1 HIGH PERFORMANCE BALLOON CATHETER/COMPONENT BOSTON SCIENTIFIC LIMITED (BB) 2006-02-16 WO disclosed
US-20060008606-A1 High performance balloon catheter/component SCIMED LIFE SYSTEMS, INC. (US) 2006-01-12 US disclosed
WO-2005007375-A2 MEDICAL DEVICES AND PROCESSES FOR PREPARING SAME BOSTON SCIENTIFIC LIMITED (BB) 2005-01-27 WO disclosed
US-20050015046-A1 Medical devices and processes for preparing same SCIMED LIFE SYSTEMS, INC. (US) 2005-01-20 US disclosed
EP-0249365-A2 Photocatalysts for vinyl compounds activated by an electron donating hetero atom LOCTITE (IRELAND) Ltd. (IE) 1987-12-16 EP disclosed