SCHEMBL3674951

SCHEMBL3674951

CC(C)Nc1nccc(O)n1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 4/20 0.49
MAPK8 P45983 3/20 0.47
ABL1 P00519 1/20 0.41
LCK P06239 1/20 0.41
CSF1R P07333 1/20 0.41
PDGFRB P09619 1/20 0.41
MAP2K2 P36507 1/20 0.41
CDK7 P50613 1/20 0.41
MAPK9 P45984 3/20 0.40
MAPK10 P53779 3/20 0.40
ACACB O00763 1/20 0.39
KCNH3 Q9ULD8 2/20 0.39
FLT3 P36888 1/20 0.38
TDP1 Q9NUW8 2/20 0.38
GAA P10253 1/20 0.38
RPS6KA3 P51812 1/20 0.37
IDO1 P14902 1/20 0.37
PDE4B Q07343 1/20 0.36
PDE10A Q9Y233 1/20 0.36
HTR7 P34969 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2844731 0.78 ABL1 (0.52) HRH4MAPK8ABL1LCKCSF1R
SCHEMBL91488 0.78 HRH4 (0.50) HRH4MAPK8ABL1LCKCSF1R
SCHEMBL3675383 0.77
SCHEMBL14999425 0.76 HRH4 (0.49) HRH4MAPK8ABL1LCKCSF1R
SCHEMBL84413 0.76 HRH4 (0.49) HRH4MAPK8ABL1LCKCSF1R
SCHEMBL4644412 0.76 HRH4 (0.49) HRH4MAPK8ABL1LCKCSF1R
SCHEMBL12411105 0.76 HRH4 (0.45) HRH4MAPK8ABL1LCKCSF1R
SCHEMBL12411106 0.74 ABL1 (0.50) HRH4MAPK8ABL1LCKCSF1R
SCHEMBL4162522 0.74 IDH1 (0.34) HRH4MAPK8LCKHTR7
SCHEMBL24650224 0.73 SYK (0.47) HRH4MAPK8ABL1LCKCSF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1877481-B1 STABILISER COMPOSITION FOR HALIDE-CONTAINING POLYMERS SUN ACE KAKOH PTE LTD (SG) 2016-02-17 EP disclosed
US-7842743-B2 Stabiliser composition for halide-containing polymers SUN ACE KAKOH (PTE.) LTD. (SG) 2010-11-30 US disclosed
US-20090030123-A1 STABILISER COMPOSITION FOR HALIDE-CONTAINING POLYMERS SUN ACE KAKOH (PTE.) LTD. (SG) 2009-01-29 US disclosed
EP-1877481-A2 STABILISER COMPOSITION FOR HALIDE-CONTAINING POLYMERS Sun Ace Kakoh (Pte.) Ltd. (SG) 2008-01-16 EP disclosed
WO-2006110112-A2 STABILISER COMPOSITION FOR HALIDE-CONTAINING POLYMERS SUN ACE KAKOH (PTE.) LTD. (SG) 2006-10-19 WO disclosed