Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 2/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.45 |
| ▸ | IDH1 | O75874 | 4/20 | 0.40 |
| ▸ | IDH2 | P48735 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.40 |
| ▸ | CDK7 | P50613 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12411108 | 0.86 | IDH1 (0.50) | SYKHRH4MAPK8IDH1IDH2 | |
| SCHEMBL10219318 | 0.84 | HTR7 (0.53) | SYKIDH1LCKMEN1KMT2A | |
| SCHEMBL8000248 | 0.84 | IDH1 (0.53) | SYKHRH4MAPK8IDH1IDH2 | |
| SCHEMBL84157 | 0.79 | SYK (0.50) | SYKCDK7MAPK9MEN1ALDH1A1 | |
| SCHEMBL15181297 | 0.77 | HRH4 (0.51) | SYKHRH4IDH1ACACB | |
| SCHEMBL18898329 | 0.76 | MAPK8 (0.39) | SYKHRH4MAPK8IDH1IDH2 | |
| SCHEMBL91488 | 0.75 | HRH4 (0.50) | HRH4MAPK8ABL1LCKCSF1R | |
| SCHEMBL2844731 | 0.75 | ABL1 (0.52) | HRH4MAPK8ABL1LCKCSF1R | |
| SCHEMBL14999425 | 0.73 | HRH4 (0.49) | HRH4MAPK8ABL1LCKCSF1R | |
| SCHEMBL3674951 | 0.73 | HRH4 (0.49) | HRH4MAPK8ABL1LCKCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11466013-B2 | ERK inhibitor and use thereof | BETTA PHARMACEUTICALS CO., LTD (CN) | 2022-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11466013-B2 | ERK inhibitor and use thereof | MAPK1, MAPK4, MAPK7 | SYK 487/4885HRH4 4245/4885MAPK8 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.