Sugi Predict

Sugi Predict / Compounds / SCHEMBL3675283

SCHEMBL3675283

SCHEMBL3675283

O=S(=O)(c1ccc(Oc2cccc(S(=O)(=O)c3cccc(Br)c3)c2)cc1)c1cccc(Br)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PGR P06401 6/20 0.57
▸ HTT P42858 3/20 0.56
▸ L3MBTL1 Q9Y468 2/20 0.56
▸ TDP1 Q9NUW8 1/20 0.56
▸ SMN1; SMN2 Q16637 1/20 0.50
▸ POLB P06746 1/20 0.42
▸ APEX1 P27695 1/20 0.42
▸ CTDSP1 Q9GZU7 1/20 0.42
▸ SOS1 Q07889 1/20 0.42
▸ MMP2 P08253 1/20 0.40
▸ MMP3 P08254 1/20 0.40
▸ MMP9 P14780 1/20 0.40
▸ MMP8 P22894 1/20 0.40
▸ MMP12 P39900 1/20 0.40
▸ MMP13 P45452 1/20 0.40
▸ MMP14 P50281 1/20 0.40
▸ MMP16 P51512 1/20 0.40
▸ LMNA P02545 1/20 0.39
▸ ALDH1A1 P00352 2/20 0.39
▸ PKM P14618 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3679144 0.95 PGR (0.57) PGRHTTL3MBTL1TDP1SMN1; SMN2
SCHEMBL3669548 0.92 HTT (0.58) PGRHTTL3MBTL1TDP1SMN1; SMN2
SCHEMBL10964994 0.92 HTT (0.61) PGRHTTL3MBTL1TDP1SMN1; SMN2
SCHEMBL11300223 0.92 HTT (0.61) PGRHTTL3MBTL1TDP1SMN1; SMN2
SCHEMBL11293951 0.92 HTT (0.61) PGRHTTL3MBTL1TDP1SMN1; SMN2
SCHEMBL11300430 0.90 HTT (0.59) PGRHTTL3MBTL1TDP1SMN1; SMN2
SCHEMBL11295346 0.90 HTT (0.59) PGRHTTL3MBTL1TDP1SMN1; SMN2
SCHEMBL11292296 0.90 HTT (0.59) PGRHTTL3MBTL1TDP1SMN1; SMN2
SCHEMBL11290712 0.89 HTT (0.58) PGRHTTL3MBTL1TDP1SMN1; SMN2
SCHEMBL11291876 0.89 HTT (0.58) PGRHTTL3MBTL1TDP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1329444-B1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR CORP (JP) 2010-05-05 — — EP disclosed
EP-1138712-B1 Polyarylene copolymers and proton-conductive membrane JSR CORP (JP) 2006-01-18 — — EP disclosed
US-6933068-B2 Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same HONDA GIKEN KOGYO KABUSHIKI KAISHA (JP) 2005-08-23 — — US disclosed
US-6833426-B2 A proton-conductive membrane containing the sulfonic acid group-containing polyarylene (co)polymer JSR CORPORATION (JP) 2004-12-21 — — US disclosed
US-6812290-B2 FOR USE AS ELECTROLYTES JSR CORPORATION (JP) 2004-11-02 — — US disclosed
US-20030195301-A1 Polyarylene copolymers and proton-conductive membrane JSR CORPORATION (JP) 2003-10-16 — — US disclosed
US-20030173547-A1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR CORPORATION (JP) 2003-09-18 — — US disclosed
EP-1329444-A1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR Corporation (JP) 2003-07-23 — — EP disclosed
US-6555626-B2 Controlled amount of sulfonic acid groups; copolymer of an aromatic compound having a main chain containing electron withdrawing groups and aromatic compounds with no electron withdrawing groups; durability, strength, conductivity JSR CORPORATION (JP) 2003-04-29 — — US disclosed
US-20020172850-A1 Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same HONDA GIKEN KOGYO KABUSHIKI KAISHA, JSR CORPORATION 2002-11-21 — — US disclosed
US-20010037000-A1 Polyarylene copolymers and proton-conductive membrane JSR CORPORATION (JP) 2001-11-01 — — US disclosed
EP-1138712-A2 Polyarylene copolymers and proton-conductive membrane JSR Corporation (JP) 2001-10-04 — — EP disclosed