SCHEMBL3675386

SCHEMBL3675386

O=C=C1C=CC=NC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31150930 0.69
SCHEMBL28256650 0.65
SCHEMBL30980991 0.63
SCHEMBL8592109 0.62
SCHEMBL15727067 0.62
SCHEMBL10747404 0.62
SCHEMBL14074057 0.62
SCHEMBL9050143 0.62
SCHEMBL7365607 0.62
SCHEMBL30129407 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116444428-A Method for introducing C-14 marked ethanol group into 3-position of pyridine ring 无锡贝塔医药科技有限公司 2023-07-18 CN claimed
EP-1915149-B1 NOVEL TRIAZOLE DERIVATIVES AS GHRELIN ANALOGUE LIGANDS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS AETERNA ZENTARIS GMBH (DE) 2018-10-10 EP claimed
US-8710089-B2 Triazole derivatives as ghrelin analogue ligands of growth hormone secretagogue receptors ZENTARIS GMBH (DE) 2014-04-29 US claimed
CN-101272782-B Novel triazole derivatives as ghrelin analogue ligands of growth hormone secretagogue receptors AETERNA ZENTARIS GMBH 2012-03-14 CN claimed
US-20100331343-A1 NOVEL TRIAZOLE DERIVATIVES AS GHRELIN ANALOGUE LIGANDS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS ZENTARIS GMBH (DE) 2010-12-30 US claimed
US-20090042905-A1 TRIAZOLE DERIVATIVES AS LIGANDS OF G-PROTEIN COUPLED RECEPTORS AETERNA ZENTARIS GMBH (DE) 2009-02-12 US claimed
CN-101272782-A Novel triazole derivatives as ghrelin analogue ligands of growth hormone secretagogue receptors AETERNA ZENTARIS GMBH (DE) 2008-09-24 CN claimed
WO-2008098977-A1 NOVEL TRIAZOLE DERIVATIVES AS LIGANDS OF G-PROTEIN COUPLED RECEPTORS ÆTERNA ZENTARIS GMBH (DE) 2008-08-21 WO claimed
EP-1958631-A1 Novel triazole derivatives as ligands of G-protein coupled receptors AEterna Zentaris GmbH (DE) 2008-08-20 EP claimed
EP-1915149-A2 NOVEL TRIAZOLE DERIVATIVES AS GHRELIN ANALOGUE LIGANDS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS AEterna Zentaris GmbH (DE) 2008-04-30 EP claimed
US-20070208061-A2 NOVEL TRIAZOLE DERIVATIVES AS GHRELIN ANALOGUE LIGANDS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS ZENTARIS GMBH (DE) 2007-09-06 US claimed
EP-1757290-A1 Novel triazole derivatives as ghrelin analogue ligands of growth hormone secretagogue receptors Zentaris GmbH (DE) 2007-02-28 EP claimed
WO-2007020013-A2 NOVEL TRIAZOLE DERIVATIVES AS GHRELIN ANALOGUE LIGANDS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS ÆTERNA ZENTARIS GMBH (DE) 2007-02-22 WO claimed
US-20070037857-A1 Novel triazole derivatives as ghrelin analogue ligands of growth hormone secretagogue receptors ZENTARIS GMBH (DE) 2007-02-15 US claimed
CN-1057552-C Triphenodioxazine dyes and preparation and application of same ZENECA LTD (GB) 2000-10-18 CN claimed
CN-1088234-A Three its preparation of benzo dioxazine dyestuff and purposes ZENECA LTD (GB) 1994-06-22 CN claimed
CN-116444428-A Method for introducing C-14 marked ethanol group into 3-position of pyridine ring 无锡贝塔医药科技有限公司 2023-07-18 CN disclosed
CN-116444428-A Method for introducing C-14 marked ethanol group into 3-position of pyridine ring 无锡贝塔医药科技有限公司 2023-07-18 CN disclosed
WO-2007020013-A2 NOVEL TRIAZOLE DERIVATIVES AS GHRELIN ANALOGUE LIGANDS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS ÆTERNA ZENTARIS GMBH (DE) 2007-02-22 WO disclosed
US-20070037857-A1 Novel triazole derivatives as ghrelin analogue ligands of growth hormone secretagogue receptors ZENTARIS GMBH (DE) 2007-02-15 US disclosed