SCHEMBL3675827

SCHEMBL3675827

NC(N)c1ccccc1Br

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.47
TDO2 P48775 1/20 0.47
F2 P00734 1/20 0.39
ALDH1A1 P00352 3/20 0.38
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA4 P22748 1/20 0.37
CA6 P23280 1/20 0.37
HTT P42858 1/20 0.36
TAAR1 Q96RJ0 1/20 0.36
MAPK1 P28482 1/20 0.35
OPRL1 P41146 1/20 0.34
DPP4 P27487 2/20 0.33
CYP3A4 P08684 1/20 0.33
ALOX15 P16050 1/20 0.33
CYP2C19 P33261 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
KDM1A O60341 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3256312 0.83 IDO1 (0.47) IDO1TDO2F2ALDH1A1MAOA
SCHEMBL24017066 0.83 IDO1 (0.47) IDO1TDO2F2ALDH1A1MAOA
SCHEMBL3250239 0.83 IDO1 (0.47) IDO1TDO2F2ALDH1A1MAOA
SCHEMBL3171505 0.81 IDO1 (0.45) IDO1TDO2F2ALDH1A1MAOA
SCHEMBL1454663 0.79 CYP3A4 (0.45) IDO1TDO2ALDH1A1MAOAMAOB
SCHEMBL31150950 0.79 CYP3A4 (0.45) IDO1TDO2ALDH1A1MAOAMAOB
SCHEMBL31151007 0.79 CYP3A4 (0.45) IDO1TDO2ALDH1A1MAOAMAOB
SCHEMBL1345820 0.79 CYP3A4 (0.45) IDO1TDO2ALDH1A1MAOAMAOB
SCHEMBL1132337 0.79 CYP3A4 (0.45) IDO1TDO2ALDH1A1MAOAMAOB
SCHEMBL2915839 0.78 F2 (0.50) F2MAOATAAR1DPP4CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1426392-B1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL CO (JP) 2010-02-24 EP disclosed
US-6960640-B2 Composition for optical material MITSUBISHI GAS CHEMICAL CO., LTD. (JP) 2005-11-01 US disclosed
US-20040147708-A1 Composition for optical material MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-07-29 US disclosed
EP-1426392-A1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-06-09 EP disclosed