SCHEMBL1132337

SCHEMBL1132337

CC(N)c1ccccc1Br

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.45
CYP2D6 P10635 2/20 0.45
CYP1A2 P05177 1/20 0.45
NFKB1 P19838 1/20 0.45
PNMT P11086 1/20 0.45
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
IDO1 P14902 1/20 0.44
TDO2 P48775 1/20 0.44
ALDH1A1 P00352 4/20 0.43
LMNA P02545 2/20 0.43
GLA P06280 1/20 0.43
HTT P42858 1/20 0.42
ADRA2A P08913 1/20 0.38
ADRA2C P18825 1/20 0.38
HIF1A Q16665 1/20 0.38
KDM4E B2RXH2 1/20 0.38
ALOX15 P16050 1/20 0.38
CYP2C19 P33261 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31150950 1.00 CYP3A4 (0.45) CYP3A4CYP2D6CYP1A2NFKB1PNMT
SCHEMBL31151007 1.00 CYP3A4 (0.45) CYP3A4CYP2D6CYP1A2NFKB1PNMT
SCHEMBL1454663 1.00 CYP3A4 (0.45) CYP3A4CYP2D6CYP1A2NFKB1PNMT
SCHEMBL1345820 1.00 CYP3A4 (0.45) CYP3A4CYP2D6CYP1A2NFKB1PNMT
Hydrochloric Acid SCHEMBL28934782 0.98 IDO1 (0.47) CYP3A4CYP2D6CYP1A2NFKB1PNMT
Hydrochloric Acid SCHEMBL30268799 0.98 IDO1 (0.47) CYP3A4CYP2D6CYP1A2NFKB1PNMT
Hydrochloric Acid SCHEMBL14120766 0.98 IDO1 (0.47) CYP3A4CYP2D6CYP1A2NFKB1PNMT
Iodide SCHEMBL28685281 0.98 CYP3A4 (0.43) CYP3A4CYP2D6CYP1A2NFKB1PNMT
SCHEMBL5846481 0.86 MAOA (0.46) CYP3A4CYP2D6CYP1A2NFKB1PNMT
SCHEMBL14395925 0.81 CYP2D6 (0.54) CYP3A4CYP2D6CYP1A2NFKB1PNMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117924207-A Epoxy resin flexible film with high glass transition temperature 中国科学院深圳先进技术研究院 2024-04-26 CN claimed
CN-117859209-A Perovskite solar cell and preparation method thereof 宁德时代新能源科技股份有限公司 2024-04-09 CN claimed
CN-117342958-A Buried interface material and flexible perovskite solar cell prepared from buried interface material 武汉理工大学 2024-01-05 CN claimed
WO-2023216132-A1 PEROVSKITE SOLAR CELL AND PREPARATION METHOD THEREFOR 宁德时代新能源科技股份有限公司 2023-11-16 WO claimed
CN-116948646-A Super-wetting buffer oxide etching solution, preparation method and application thereof 浙江奥首材料科技有限公司 2023-10-27 CN claimed
CN-114011374-B Fast-suction non-evaporable titanium-molybdenum getter 安徽有研吸气材料有限公司 2023-07-14 CN claimed
CN-112724084-B Preparation method of (S) -5-bromo-1, 2,3, 4-tetrahydro-N-Boc-isoquinoline-1-carboxylic acid 上海彩迩文生化科技有限公司 2022-04-22 CN claimed
CN-114011374-A Non-evaporable titanium-molybdenum getter capable of rapidly absorbing air 安徽有研吸气材料有限公司 2022-02-08 CN claimed
CN-112724084-A Preparation method of (S) -5-bromo-1, 2,3, 4-tetrahydro-N-Boc-isoquinoline-1-carboxylic acid 南京艾普特生物医药有限公司 2021-04-30 CN claimed
EP-4662204-A2 TELOMERASE INHIBITOR COMPOUNDS Geron Corporation (US) 2025-12-17 EP disclosed
CN-120590906-A Bi-component reworkable heat conducting adhesive for power battery and preparation method thereof 江苏中迪新材料技术有限公司 2025-09-05 CN disclosed
CN-115677616-B Macrocyclic sulfonamide compound, preparation method and medical application thereof 中国药科大学 2024-10-18 CN disclosed
US-20240343713-A1 TELOMERASE INHIBITOR COMPOUNDS BIOPHARMA CREDIT PLC [COLLATERAL AGENT] (GB) 2024-10-17 US disclosed
CN-110891951-B Compounds of formula (I) 谢菲尔德大学 2024-08-20 CN disclosed
EP-0418399-B1 COMPOSITION FOR REVERSIBLE THERMAL RECORDING MEDIUM TOPPAN PRINTING CO LTD (JP) 1996-08-28 EP disclosed
EP-0688679-A1 Method for reversible thermosensitive recording Toppan Printing Co., Ltd. (JP) 1995-12-27 EP disclosed
US-5178669-A COMPOSITION FOR REVERSIBLE THERMAL RECORDING MEDIA TOPPAN PRINTING CO., LTD. (JP) 1993-01-12 US disclosed
EP-0418399-A1 COMPOSITION FOR REVERSIBLE THERMAL RECORDING MEDIUM Toppan Printing Co., Ltd. (JP) 1991-03-27 EP disclosed
US-4956346-A URIDINE DERIVATIVES AS VIRICIDES HOFFMANN-LA ROCHE INC. (US) 1990-09-11 US disclosed
US-4886785-A VIRICIDES, HERPES SIMPLEX HOFFMANN-LA ROCHE INC. (US) 1989-12-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240343713-A1 TELOMERASE INHIBITOR COMPOUNDS TERT, POT1, TERF2 CYP3A4 2759/4885CYP2D6 3901/4885CYP1A2 2897/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.