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Formic Acid

Formic Acid

SCHEMBL3676038

COC1CCN(c2ccccc2S(=O)(=O)n2ccc3c(N4CCNCC4)cccc32)C1.O=CO

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ HTR6 P50406 19/20 0.58
▸ HTR1A P08908 1/20 0.43
▸ DRD2 P14416 1/20 0.43
▸ HTR2A P28223 1/20 0.43
▸ FABP4 P15090 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5008022 0.96 HTR6 (0.63) HTR6HTR1ADRD2HTR2A
Formic Acid SCHEMBL3679749 0.86 HTR6 (0.57) HTR6HTR1ADRD2HTR2A
Formic Acid SCHEMBL3679742 0.86 HTR6 (0.57) HTR6HTR1ADRD2HTR2A
SCHEMBL5005901 0.82 HTR6 (0.63) HTR6HTR1ADRD2HTR2A
SCHEMBL5005906 0.82 HTR6 (0.63) HTR6HTR1ADRD2HTR2A
SCHEMBL3670406 0.81 HTR6 (0.61) HTR6HTR1ADRD2HTR2A
SCHEMBL3670408 0.81 HTR6 (0.61) HTR6HTR1ADRD2HTR2A
SCHEMBL13993619 0.81 HTR6 (0.61) HTR6HTR1ADRD2HTR2A
SCHEMBL3676041 0.80 HTR6 (0.46) HTR6
SCHEMBL3624639 0.77 HTR6 (0.45) HTR6HTR1AHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2162433-A2 4' SUBSTITUTED COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY Memory Pharmaceuticals Corporation (US) 2010-03-17 — — EP disclosed
WO-2008147812-A2 4' SUBSTITUTED COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY MEMORY PHARMACEUTICALS CORPORATION (US) 2008-12-04 — — WO disclosed